SNRNP200

Gene Symbol SNRNP200
Entrez Gene 23020
Alt Symbol ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein 200kDa (U5)
Other Description BRR2 homolog|U5 small nuclear ribonucleoprotein 200 kDa helicase|U5 snRNP-specific 200 kDa protein|activating signal cointegrator 1 complex subunit 3-like 1
Swissprots Q9H7S0 O94884 Q6PX59 Q6NZY0 Q96IF2 O75643 Q8NBE6
Accessions CAA94089 EAW71372 EAW71373 O75643 AB018331 BAA34508 AF085356 AAD40191 AF119874 AAF69628 AJ844618 CAH59741 AK021418 AK021583 AK023840 BAB14698 AK024391 BAB14906 AK026662 AK090671 BAC03499 AK303465 BAG64507 AK303663 BAG64662 AL831994 AW190145 AY572488 AAS78571 BC001417 AAH01417 BC007577 AAH07577 BC065924 AAH65924 BC112891 AAI12892 BC131784 AAI31785 BP873066 DA109508 DB067751 NM_014014 NP_054733
Function RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. {ECO:0000269|PubMed:16723661, ECO:0000269|PubMed:23045696, ECO:0000269|PubMed:8670905, ECO:0000269|PubMed:9539711}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9539711}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:19878916}.
Top Pathways Spliceosome

Panoply™ Human SNRNP200 Knockdown Stable Cell Line - CSC-DC014814 from Creative biogene

Category Cell Line
Species Human
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