Gene Symbol | EIF2D |
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Entrez Gene | 1939 |
Alt Symbol | HCA56, LGTN |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 2D |
Other Description | hepatocellular carcinoma-associated antigen 56|ligatin |
Swissprots | Q9NSN0 Q9NR27 Q8IXV3 Q9NZ21 Q5SY40 Q96TG7 Q96DG3 P41214 Q9NV18 |
Accessions | EAW93536 EAW93537 EAW93538 EAW93539 EAW93540 P41214 AB209364 BAD92601 AF159586 AAD41909 AF220417 AAF34185 AF262403 AAF74205 AK001852 BAA91942 AK225259 AK294536 BAG57743 AL162001 CAB82330 BC001585 AAH01585 BC039134 AAH39134 BC058905 AAH58905 BI465059 DC399556 DQ580499 DQ891590 ABM82516 DQ894784 ABM85710 XM_005277509 XP_005277566 XM_006711196 XP_006711259 XM_011509257 XP_011507559 XM_011509258 XP_011507560 XR_921750 XR_921751 NM_001201478 NP_001188407 NM_006893 NP_008824 |
Function | Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P- site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. {ECO:0000269|PubMed:20566627, ECO:0000269|PubMed:20713520}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20566627}. |
Human EIF2D full length protein - ab132827 from Abcam
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Human EIF2D protein fragment - ab116939 from Abcam
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LGTN / EIF2D Antibody Blocking Peptide - LS-E14904 from LifeSpan Bioscience
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Recombinant Human LGTN Protein - H00001939-Q01 from Novus Biologicals
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Recombinant Human LGTN Protein - H00001939-P01 from Novus Biologicals
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LGTN-Antibody-N-term-Blocking-peptide - BP12096a from Abgent, a WuXi AppTec company
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Ligatin Blocking Peptide - 33R-4725 from Fitzgerald
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Ligatin - H00001939-P01-10 from Acris Antibodies
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Ligatin - H00001939-P01-25 from Acris Antibodies
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Ligatin - H00001939-Q01-10 from Acris Antibodies
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Ligatin - H00001939-Q01-25 from Acris Antibodies
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LGTN fusion protein - Ag3579 from Proteintech Group
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Recombinant Human EIF2D - EIF2D-28492TH from Creative Biomart
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Recombinant Human Eukaryotic translation initiation factor 2D(EIF2D) - CSB-YP012909HU CSB-EP012909HU CSB-BP012909HU CSB-MP012909HU from Cusabio
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LGTN Protein - abx164886 from Abbexa
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Recombinant Eukaryotic translation initiation factor 2D (EIF2D) - RPC565Hu01 from Cloud-clone
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Recombinant Eukaryotic translation initiation factor 2D (EIF2D) - RPC565Hu01 from Uscn Life Science Inc.
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Recombinant Eukaryotic translation initiation factor 2D (EIF2D) - RPC565Mu01 from Uscn Life Science Inc.
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Recombinant Eukaryotic translation initiation factor 2D (EIF2D) - RPC565Ra01 from Uscn Life Science Inc.
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Ligatin - TP301726 from Acris Antibodies
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LGTN Recombinant Protein Antigen - NBP1-81308PEP from Novus Biologicals
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EIF2D Peptide, Human - M34GP04808H from Creative Peptides
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Recombinant Eukaryotic translation initiation factor 2D (EIF2D) - RPU51933 from Biomatik
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EIF2D Recombinant Protein (OPCD02883) - OPCD02883 from Aviva Systems Biology
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Eukaryotic translation initiation factor 2D, Recombinant Protein - MBS2033206 from MyBioSource
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