NACC1

Gene Symbol	NACC1
Entrez Gene	112939
Alt Symbol	BEND8, BTBD14B, BTBD30, NAC-1, NAC1
Species	Human
Gene Type	protein-coding
Description	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
Other Description	BEN domain containing 8|BTB/POZ domain-containing protein 14B|nucleus accumbens-associated protein 1|transcriptional repressor NAC1
Swissprots	Q96RE7
Accessions	EAW84352 EAW84353 EAW84354 Q96RE7 AF395817 AAK83885 AK094702 AK123056 AK226064 BC055396 AAH55396 BU508302 BU623112 BX395451 XM_005259721 XP_005259778 NM_052876 NP_443108
Function	Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. {ECO:0000269|PubMed:17130457, ECO:0000269|PubMed:17804717}.
Subcellular Location	Nucleus. Cytoplasm. Note=Distribution in the cytoplasm is dependent on phosphorylation. {ECO:0000250}.
Tissue Specificity	Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer. {ECO:0000269|PubMed:17130457, ECO:0000269|PubMed:17391728}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NACC1 / NAC1 Antibody Blocking Peptide - LS-E12319 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NACC1 / NAC1 Antibody Blocking Peptide - LS-E26303 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAC1 blocking peptide - GTX89124-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

Nac1 Peptide - AC21-1135-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NAC1 Peptide - 45-930P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

NACC1 fusion protein - Ag6096 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NACC1 fusion protein - ag6468 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NACC1, GST-tagged - NACC1-1168H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Nucleus accumbens-associated protein 1(NACC1) - CSB-YP836291HU CSB-EP836291HU CSB-BP836291HU CSB-MP836291HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NAC1/BTBD14B, Peptide - MBS426493 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog

NAC1 Protein - NBP1-89991PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NAC1 Recombinant Protein Antigen - NBP2-49361PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

BTBD14B-Antibody-C-term-Blocking-Peptide - BP1593b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Nac1-BTBD14B-Antibody-Center-Blocking-peptide - BP1493c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Nac1-Antibody-C-term-Blocking-peptide - BP1493b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NACC1-Blocking-Peptide-Center - BP21031a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NACC1-Blocking-Peptide-C-term - BP21107a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NACC1 Peptide, Human - M34GP10095H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nucleus accumbens-associated protein 1 (NACC1), Recombinant Protein - MBS1459783 from MyBioSource Category Protein Prices $1,320.00, $1,320.00, $1,535.00, $1,535.00, $2,175.00, $2,175.00, $2,640.00, $2,640.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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