| Gene Symbol |
MED19
|
| Entrez Gene |
219541
|
| Alt Symbol |
DT2P1G7, LCMR1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 19
|
| Other Description |
lung cancer metastasis-related protein 1|mediator of RNA polymerase II transcription subunit 19|mediator of RNA polymerase II transcription, subunit 19 homolog
|
| Swissprots |
Q8IV02 A0JLT2 Q8IZD1
|
| Accessions |
A0JLT2 EAW73774 EAW73775 EAW73776 AY148462 AAN16075 BC009723 AAH09723 BC037223 AAH37223 HE646678 CCF17579 U92995 XM_005273821 XP_005273878 NM_153450 NP_703151
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
![Western Blot: MED19 Overexpression Lysate (Adult Normal) [NBL1-12984] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED19.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11951_MED19%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12984-img0002.jpg)