Gene Symbol | MED19 |
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Entrez Gene | 219541 |
Alt Symbol | DT2P1G7, LCMR1 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 19 |
Other Description | lung cancer metastasis-related protein 1|mediator of RNA polymerase II transcription subunit 19|mediator of RNA polymerase II transcription, subunit 19 homolog |
Swissprots | Q8IV02 A0JLT2 Q8IZD1 |
Accessions | A0JLT2 EAW73774 EAW73775 EAW73776 AY148462 AAN16075 BC009723 AAH09723 BC037223 AAH37223 HE646678 CCF17579 U92995 XM_005273821 XP_005273878 NM_153450 NP_703151 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Med19 CRISPR/Cas9 KO Plasmid (h) - sc-415065 from Santa Cruz Biotechnology
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Med19 HDR Plasmid (h) - sc-415065-HDR from Santa Cruz Biotechnology
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Med19 Double Nickase Plasmid (h) - sc-415065-NIC from Santa Cruz Biotechnology
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Med19 Double Nickase Plasmid (h2) - sc-415065-NIC-2 from Santa Cruz Biotechnology
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Med19 CRISPR Activation Plasmid (h) - sc-415065-ACT from Santa Cruz Biotechnology
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Med19 CRISPR Activation Plasmid (h2) - sc-415065-ACT-2 from Santa Cruz Biotechnology
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Med19 Lentiviral Activation Particles (h) - sc-415065-LAC from Santa Cruz Biotechnology
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Med19 Lentiviral Activation Particles (h2) - sc-415065-LAC-2 from Santa Cruz Biotechnology
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Med19 siRNA (h) - sc-96437 from Santa Cruz Biotechnology
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Med19 shRNA Plasmid (h) - sc-96437-SH from Santa Cruz Biotechnology
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Med19 shRNA (h) Lentiviral Particles - sc-96437-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13168 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13168 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06963 from Sigma-Aldrich
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MED19 siRNA (Human) - CRJ6395 from Cohesion Biosciences
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shRNA set against Human MED19 (NM_153450.1) - SHH339963 from Creative biogene
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shRNA set against Human MED19(NM_153450.1) - SHH183467 from Creative biogene
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MED19 shRNA Plasmid (Human) - CHJ6395 from Cohesion Biosciences
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MED19 miRNA 3'UTR clone - MiUTR1H-06189 from Creative biogene
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