| Gene Symbol |
EPN3
|
| Entrez Gene |
55040
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
epsin 3
|
| Other Description |
EPS-15-interacting protein 3|epsin-3
|
| Swissprots |
A8K6J3 Q9NWK2 A8KAB2 Q9H201 Q9BVN6
|
| Accessions |
EAW94606 EAW94607 Q9H201 AF324241 AAG45223 AK000785 BAA91378 AK291658 BAF84347 AK292977 BAF85666 AK295730 BAG58571 AK296346 BAG59030 AK300642 BAG62331 BC001038 BC051365 BC077722 BC110602 AAI10603 BC110605 AAI10606 BM981734 BU539570 CA944655 DA392550 DC388544 NM_017957 NP_060427
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11359770}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11359770}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:11359770}. Nucleus {ECO:0000305|PubMed:11359770}. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
|
| Tissue Specificity |
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis. {ECO:0000269|PubMed:11359770}.
|
| Top Pathways |
Endocytosis
|
![Western Blot: Epsin 3 Overexpression Lysate (Adult Normal) [NBP2-06890] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Epsin 3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1664_Epsin%25203%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06890-img0001.jpg)