Gene Symbol |
EPN3
|
Entrez Gene |
55040
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
epsin 3
|
Other Description |
EPS-15-interacting protein 3|epsin-3
|
Swissprots |
A8K6J3 Q9NWK2 A8KAB2 Q9H201 Q9BVN6
|
Accessions |
EAW94606 EAW94607 Q9H201 AF324241 AAG45223 AK000785 BAA91378 AK291658 BAF84347 AK292977 BAF85666 AK295730 BAG58571 AK296346 BAG59030 AK300642 BAG62331 BC001038 BC051365 BC077722 BC110602 AAI10603 BC110605 AAI10606 BM981734 BU539570 CA944655 DA392550 DC388544 NM_017957 NP_060427
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11359770}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11359770}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:11359770}. Nucleus {ECO:0000305|PubMed:11359770}. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
|
Tissue Specificity |
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis. {ECO:0000269|PubMed:11359770}.
|
Top Pathways |
Endocytosis
|