Gene Symbol | EPN3 |
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Entrez Gene | 55040 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | epsin 3 |
Other Description | EPS-15-interacting protein 3|epsin-3 |
Swissprots | A8K6J3 Q9NWK2 A8KAB2 Q9H201 Q9BVN6 |
Accessions | EAW94606 EAW94607 Q9H201 AF324241 AAG45223 AK000785 BAA91378 AK291658 BAF84347 AK292977 BAF85666 AK295730 BAG58571 AK296346 BAG59030 AK300642 BAG62331 BC001038 BC051365 BC077722 BC110602 AAI10603 BC110605 AAI10606 BM981734 BU539570 CA944655 DA392550 DC388544 NM_017957 NP_060427 |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11359770}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11359770}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:11359770}. Nucleus {ECO:0000305|PubMed:11359770}. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. |
Tissue Specificity | Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis. {ECO:0000269|PubMed:11359770}. |
Top Pathways | Endocytosis |
epsin 3 CRISPR/Cas9 KO Plasmid (h) - sc-409987 from Santa Cruz Biotechnology
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epsin 3 HDR Plasmid (h) - sc-409987-HDR from Santa Cruz Biotechnology
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epsin 3 Double Nickase Plasmid (h) - sc-409987-NIC from Santa Cruz Biotechnology
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epsin 3 Double Nickase Plasmid (h2) - sc-409987-NIC-2 from Santa Cruz Biotechnology
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epsin 3 CRISPR Activation Plasmid (h) - sc-409987-ACT from Santa Cruz Biotechnology
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epsin 3 CRISPR Activation Plasmid (h2) - sc-409987-ACT-2 from Santa Cruz Biotechnology
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epsin 3 Lentiviral Activation Particles (h) - sc-409987-LAC from Santa Cruz Biotechnology
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epsin 3 Lentiviral Activation Particles (h2) - sc-409987-LAC-2 from Santa Cruz Biotechnology
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epsin 3 siRNA (h) - sc-93806 from Santa Cruz Biotechnology
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epsin 3 shRNA Plasmid (h) - sc-93806-SH from Santa Cruz Biotechnology
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epsin 3 shRNA (h) Lentiviral Particles - sc-93806-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU123351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7928 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7928 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05352 from Sigma-Aldrich
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EPN3 siRNA (Human) - CRJ0428 from Cohesion Biosciences
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Epsin 3 RNAi - H00055040-R01 from Novus Biologicals
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EPN3 - MBS8214435 from MyBioSource
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shRNA set against Human EPN3 (NM_017957.2) - SHH286593 from Creative biogene
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shRNA set against Human EPN3(NM_017957.2) - SHH036839 from Creative biogene
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Human EPN3 siRNA - orb270929 from Biorbyt
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EPN3 shRNA Plasmid (Human) - CHJ0428 from Cohesion Biosciences
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EPN3 miRNA 3'UTR clone - MiUTR1H-03272 from Creative biogene
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