Gene Symbol | TECPR1 |
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Entrez Gene | 25851 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | tectonin beta-propeller repeat containing 1 |
Other Description | tectonin beta-propeller repeat-containing protein 1 |
Swissprots | C9J024 A8KAD1 B3KPZ1 Q9P2I9 Q7Z6L1 F5GX57 Q96EB0 Q9UFR6 |
Accessions | EAL23891 EAL23892 EAW76716 EAW76717 EAW76718 Q7Z6L1 AB037779 BAA92596 AK027072 AK057048 BAG51853 AK057618 AK075074 AK292996 BAF85685 AL117495 CAB55961 BC012529 AAH12529 BC053591 AAH53591 BE616972 BQ009108 DA336445 XM_005250253 XP_005250310 XR_428174 NM_015395 NP_056210 |
Function | Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation. {ECO:0000269|PubMed:21575909, ECO:0000269|PubMed:22342342}. |
Subcellular Location | Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes. |
TECPR1 (D6C10) Rabbit mAb - 8097 from Cell Signaling Technology
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TECPR1 (S-13) - sc-240971 from Santa Cruz Biotechnology
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Anti-TECPR1 antibody - ab92384 from Abcam
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Anti-TECPR1 antibody - ab91234 from Abcam
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Anti-TECPR1 antibody - ab168320 from Abcam
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Anti-TECPR1 Antibody (N-Terminus, AP) - LS-C246120 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus, APC) - LS-C246121 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus, Biotin) - LS-C246123 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus, FITC) - LS-C246124 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus, PE) - LS-C246125 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus, Azide-free, HRP) - LS-C247920 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (N-Terminus) - LS-C328858 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (aa69-118) - LS-C206028 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (aa1094-1122) - LS-C100584 from LifeSpan Bioscience
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Anti-TECPR1 Antibody (aa162-189) - LS-C163348 from LifeSpan Bioscience
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TECPR1 Antibody - NBP1-84206 from Novus Biologicals
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TECPR1 Antibody - H00025851-B01 from Novus Biologicals
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Anti-TECPR1 antibody produced in rabbit - HPA021061 from Sigma-Aldrich
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ANTI-TECPR1 (C-TERM) antibody produced in rabbit - SAB1303058 from Sigma-Aldrich
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ANTI-PALA (N-TERM) antibody produced in rabbit - SAB1303056 from Sigma-Aldrich
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TECPR1 Antibody - N-terminal region (ARP71734_P050) - ARP71734_P050 from Aviva Systems Biology
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PALA-Antibody-N-term - AP6845a from Abgent, a WuXi AppTec company
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TECPR1-Antibody-C-term - AP7391b from Abgent, a WuXi AppTec company
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TECPR1 Antibody - N-terminal region (OAAB03948) - OAAB03948 from Aviva Systems Biology
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TECPR1 Antibody - C-terminal region (OAAB04411) - OAAB04411 from Aviva Systems Biology
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