Gene Symbol | DRD1 |
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Entrez Gene | 1812 |
Alt Symbol | DADR, DRD1A |
Species | Human |
Gene Type | protein-coding |
Description | dopamine receptor D1 |
Other Description | D(1A) dopamine receptor|dopamine D1 receptor |
Swissprots | Q4QRJ0 P21728 B2RA44 |
Accessions | AAB26273 BAC05902 CAA39284 CAA39286 EAW61376 EAW61377 P21728 AF498961 AAM18131 AK314031 BAG36741 BC074978 AAH74978 BC074979 AAH74979 BC096837 AAH96837 CR541922 CAG46720 DA249160 X58987 CAA41734 NM_000794 NP_000785 |
Function | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. {ECO:0000250}. |
Tissue Specificity | Detected in caudate, nucleus accumbens and in the olfactory tubercle. {ECO:0000269|PubMed:2144334}. |
Top Pathways | Amphetamine addiction, cAMP signaling pathway, Alcoholism, Cocaine addiction, Morphine addiction |
D1DR (E-16) - sc-31479 from Santa Cruz Biotechnology
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D1DR (G-18) - sc-31478 from Santa Cruz Biotechnology
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D1DR (C-20) - sc-1434 from Santa Cruz Biotechnology
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D1DR (H-109) - sc-14001 from Santa Cruz Biotechnology
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D1DR (SG2-D1a) - sc-33660 from Santa Cruz Biotechnology
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Anti-Dopamine Receptor D1 antibody - ab20066 from Abcam
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Anti-Dopamine Receptor D1 antibody - ab85608 from Abcam
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Anti-Dopamine Receptor D1 antibody [EP1560Y] - ab81296 from Abcam
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Anti-Dopamine Receptor D1 antibody - C-terminal - ab151620 from Abcam
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Anti-Dopamine Receptor D1 antibody - Extracellular domain - ab150499 from Abcam
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Anti-Dopamine Receptor D1 antibody - N-terminal - ab137488 from Abcam
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Anti-DRD1 / Dopamine Receptor D1 Antibody - LS-C332275 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (aa249-446) - LS-C344034 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (C-Terminus) IHC-plus⢠- LS-A44 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (aa9-21) - LS-C22904 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (aa9-21) - LS-C22892 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (N-Terminus) - LS-C22906 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (4th Extracellular Domain) - LS-C22907 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (4th Extracellular Domain) - LS-C22908 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody - LS-C36183 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (aa403-415) - LS-C22916 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (C-Terminus, clone SG2-D1a) - LS-C22917 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody - LS-C36184 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody - LS-C36185 from LifeSpan Bioscience
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Anti-DRD1 / Dopamine Receptor D1 Antibody (aa425-436) - LS-C54732 from LifeSpan Bioscience
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