| Gene Symbol |
DRD1
|
| Entrez Gene |
1812
|
| Alt Symbol |
DADR, DRD1A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dopamine receptor D1
|
| Other Description |
D(1A) dopamine receptor|dopamine D1 receptor
|
| Swissprots |
Q4QRJ0 P21728 B2RA44
|
| Accessions |
AAB26273 BAC05902 CAA39284 CAA39286 EAW61376 EAW61377 P21728 AF498961 AAM18131 AK314031 BAG36741 BC074978 AAH74978 BC074979 AAH74979 BC096837 AAH96837 CR541922 CAG46720 DA249160 X58987 CAA41734 NM_000794 NP_000785
|
| Function |
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. {ECO:0000250}.
|
| Tissue Specificity |
Detected in caudate, nucleus accumbens and in the olfactory tubercle. {ECO:0000269|PubMed:2144334}.
|
| Top Pathways |
Amphetamine addiction, cAMP signaling pathway, Alcoholism, Cocaine addiction, Morphine addiction
|