DUSP10

Gene Symbol DUSP10
Entrez Gene 11221
Alt Symbol MKP-5, MKP5
Species Human
Gene Type protein-coding
Description dual specificity phosphatase 10
Other Description dual specificity phosphatase MKP-5|dual specificity protein phosphatase 10|map kinase phosphatase 5|mitogen-activated protein kinase phosphatase 5|serine/threonine specific protein phosphatase
Swissprots D3DTB4 Q9H9Z5 Q9Y6W6 Q6GSI4
Accessions CBI69376 CBI69577 EAW93283 EAW93284 EAW93285 EAW93286 EAW93287 Q9Y6W6 AA431025 AB026436 BAA81668 AF179212 AAD51857 AI220242 AI261880 AK022513 BAB14070 AK293287 BAG56811 BC020608 AAH20608 BC031405 AAH31405 BC063826 AAH63826 BG720911 BP222019 BQ000769 BQ082194 BQ223632 CR457092 CAG33373 DQ895257 ABM86183 EU176242 ABW03693 XM_011509115 XP_011507417 XM_011509116 XP_011507418 NM_007207 NP_009138 NR_111939 NR_111940 NM_144728 NM_144729
Function Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. {ECO:0000269|PubMed:22375048}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Detected in brain. {ECO:0000269|PubMed:16806267}.
Top Pathways MAPK signaling pathway

DUSP10/MKP5 Antibody - 3483 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from RD and rat muscle cells using DUSP10/MKP5 Antibody.

MKP-5 (G-10) - sc-374276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKP-5 (G-10): sc-374276. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

MKP-5 (D-17) - sc-47664 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKP-5 (D-17): sc-47664. Western blot analysis of MKP-5 expression in non-transfected: sc-117752 (A) and human MKP-5 transfected: sc-176156 (B) 293T whole cell lysates.

MKP-5 (H-205) - sc-135201 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MKP-5 (T-12) - sc-47665 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MKP-5 (Y-18) - sc-47666 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKP-5 (Y-18): sc-47666. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic and nuclear staining of hepatocytes.

Anti-DUSP10 antibody - ab2272 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab2272 staining (0.5µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-DUSP10 antibody - ab119950 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DUSP10 antibody (ab119950) at 1/1000 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal liver lysateLane 3 : Human fetal muscle lysate

Anti-DUSP10 antibody [EPR9366] - ab140123 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9366
Overlay histogram showing Hela cells stained with ab140123 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab140123, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-DUSP10 antibody - Aminoterminal end - ab71309 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DUSP10 antibody - Aminoterminal end (ab71309) at 1/60 dilution + mouse heart tissue lysates. at 35 µg

Anti-DUSP10 antibody - Carboxyterminal end - ab71532 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DUSP10 antibody - Carboxyterminal end (ab71532) at 1/60 dilution + CEM cell line lysate at 35 µg

Anti-DUSP10 / MKP5 Antibody (aa211-227) - LS-C147961 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, AP) - LS-C222286 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, Biotin) - LS-C222287 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, FITC) - LS-C222289 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, APC) - LS-C222288 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, Azide-free, HRP) - LS-C222290 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (N-Terminus, AP) - LS-C225246 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa204-232, PE) - LS-C222292 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (N-Terminus, APC) - LS-C225247 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (N-Terminus) - LS-C108023 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DUSP10 antibody LS-C108023 Western blot of THP-1 cell lysate.

Anti-DUSP10 / MKP5 Antibody (N-Terminus, FITC) - LS-C225249 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (N-Terminus, Azide-free, HRP) - LS-C225250 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (N-Terminus, PE) - LS-C225251 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP10 / MKP5 Antibody (aa469-482) - LS-C54744 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (0.5 ug/ml) of Human Liver lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Search more