| Gene Symbol |
DUSP10
|
| Entrez Gene |
11221
|
| Alt Symbol |
MKP-5, MKP5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dual specificity phosphatase 10
|
| Other Description |
dual specificity phosphatase MKP-5|dual specificity protein phosphatase 10|map kinase phosphatase 5|mitogen-activated protein kinase phosphatase 5|serine/threonine specific protein phosphatase
|
| Swissprots |
D3DTB4 Q9H9Z5 Q9Y6W6 Q6GSI4
|
| Accessions |
CBI69376 CBI69577 EAW93283 EAW93284 EAW93285 EAW93286 EAW93287 Q9Y6W6 AA431025 AB026436 BAA81668 AF179212 AAD51857 AI220242 AI261880 AK022513 BAB14070 AK293287 BAG56811 BC020608 AAH20608 BC031405 AAH31405 BC063826 AAH63826 BG720911 BP222019 BQ000769 BQ082194 BQ223632 CR457092 CAG33373 DQ895257 ABM86183 EU176242 ABW03693 XM_011509115 XP_011507417 XM_011509116 XP_011507418 NM_007207 NP_009138 NR_111939 NR_111940 NM_144728 NM_144729
|
| Function |
Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. {ECO:0000269|PubMed:22375048}.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Tissue Specificity |
Detected in brain. {ECO:0000269|PubMed:16806267}.
|
| Top Pathways |
MAPK signaling pathway
|
![Western Blot: DUSP10 Overexpression Lysate (Adult Normal) [NBL1-10046] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DUSP10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7538_DUSP10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10046-img0002.jpg)
![Western Blot: DUSP10 Overexpression Lysate (Adult Normal) [NBP2-05529] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DUSP10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5593_DUSP10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05529-img0001.jpg)