DUSP10
| Gene Symbol | DUSP10 |
|---|---|
| Entrez Gene | 11221 |
| Alt Symbol | MKP-5, MKP5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | dual specificity phosphatase 10 |
| Other Description | dual specificity phosphatase MKP-5|dual specificity protein phosphatase 10|map kinase phosphatase 5|mitogen-activated protein kinase phosphatase 5|serine/threonine specific protein phosphatase |
| Swissprots | D3DTB4 Q9H9Z5 Q9Y6W6 Q6GSI4 |
| Accessions | CBI69376 CBI69577 EAW93283 EAW93284 EAW93285 EAW93286 EAW93287 Q9Y6W6 AA431025 AB026436 BAA81668 AF179212 AAD51857 AI220242 AI261880 AK022513 BAB14070 AK293287 BAG56811 BC020608 AAH20608 BC031405 AAH31405 BC063826 AAH63826 BG720911 BP222019 BQ000769 BQ082194 BQ223632 CR457092 CAG33373 DQ895257 ABM86183 EU176242 ABW03693 XM_011509115 XP_011507417 XM_011509116 XP_011507418 NM_007207 NP_009138 NR_111939 NR_111940 NM_144728 NM_144729 |
| Function | Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. {ECO:0000269|PubMed:22375048}. |
| Subcellular Location | Cytoplasm. Nucleus. |
| Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:16806267}. |
| Top Pathways | MAPK signaling pathway |
MKP-5 CRISPR/Cas9 KO Plasmid (h) - sc-408196 from Santa Cruz Biotechnology
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MKP-5 HDR Plasmid (h) - sc-408196-HDR from Santa Cruz Biotechnology
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MKP-5 Double Nickase Plasmid (h) - sc-408196-NIC from Santa Cruz Biotechnology
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MKP-5 Double Nickase Plasmid (h2) - sc-408196-NIC-2 from Santa Cruz Biotechnology
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MKP-5 CRISPR Activation Plasmid (h) - sc-408196-ACT from Santa Cruz Biotechnology
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MKP-5 CRISPR Activation Plasmid (h2) - sc-408196-ACT-2 from Santa Cruz Biotechnology
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MKP-5 Lentiviral Activation Particles (h) - sc-408196-LAC from Santa Cruz Biotechnology
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MKP-5 Lentiviral Activation Particles (h2) - sc-408196-LAC-2 from Santa Cruz Biotechnology
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MKP-5 siRNA (h) - sc-61048 from Santa Cruz Biotechnology
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MKP-5 shRNA Plasmid (h) - sc-61048-SH from Santa Cruz Biotechnology
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MKP-5 shRNA (h) Lentiviral Particles - sc-61048-V from Santa Cruz Biotechnology
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DUSP10 RNAi - H00011221-R02 from Novus Biologicals
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DUSP10 RNAi - H00011221-R03 from Novus Biologicals
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DUSP10 RNAi - H00011221-R01 from Novus Biologicals
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MISSION® esiRNA - EHU124481 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0091 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0939 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0938 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0092 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0093 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7542 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7542 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07974 from Sigma-Aldrich
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DUSP10 siRNA (Human) - CRH7689 from Cohesion Biosciences
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DUSP10 - MBS8214204 from MyBioSource
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