TPRKB

Gene Symbol TPRKB
Entrez Gene 51002
Alt Symbol CGI-121
Species Human
Gene Type protein-coding
Description TP53RK binding protein
Other Description EKC/KEOPS complex subunit TPRKB|PRPK (p53-related protein kinase)-binding protein|PRPK-binding protein|TP53RK-binding protein
Swissprots Q8IWR7 Q8IWR6 D6W5H6 Q9Y3C4 Q9H3K4
Accessions CAJ42830 EAW99720 EAW99721 EAW99722 EAW99723 Q9Y3C4 AF060921 AAG43133 AF151879 AAD34116 AI759966 AK097254 AK291071 BAF83760 AK295239 BAG58232 AY157986 AAN76356 AY157987 AAN76357 AY643713 AAT64915 BC029492 AAH29492 DA688967 XM_005264343 XP_005264400 XM_005264345 XP_005264402 XM_006712026 XP_006712089 XM_006712027 XP_006712090 XM_011532877 XP_011531179 XM_011532878 XP_011531180 XM_011532879 XP_011531181 XM_011532880 XP_011531182 NM_016058 NP_057142
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:12659830}.

CGI-121 CRISPR/Cas9 KO Plasmid (h) - sc-417329 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 HDR Plasmid (h) - sc-417329-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 Double Nickase Plasmid (h) - sc-417329-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 Double Nickase Plasmid (h2) - sc-417329-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 CRISPR Activation Plasmid (h) - sc-417329-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 CRISPR Activation Plasmid (h2) - sc-417329-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 Lentiviral Activation Particles (h) - sc-417329-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 Lentiviral Activation Particles (h2) - sc-417329-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CGI-121 siRNA (h) - sc-94603 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CGI-121 shRNA Plasmid (h) - sc-94603-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CGI-121 shRNA (h) Lentiviral Particles - sc-94603-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPRKB RNAi - H00051002-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU074301 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21882 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21882 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TPRKB siRNA (Human) - CRH9444 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPRKB - MBS8202727 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TPRKB (NM_016058.2) - SHH433492 from Creative biogene

Category siRNA
Species Reactivities Human

Human TPRKB siRNA - orb269946 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPRKB shRNA Plasmid (Human) - CHH9444 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TPRKB miRNA 3'UTR clone - MiUTR3H-10148 from Creative biogene

Species Reactivities Human
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