TSEN54

Gene Symbol TSEN54
Entrez Gene 283989
Alt Symbol PCH2A, PCH4, PCH5, SEN54L, sen54
Species Human
Gene Type protein-coding
Description TSEN54 tRNA splicing endonuclease subunit
Other Description SEN54 homolog|hsSen54|tRNA-intron endonuclease Sen54|tRNA-splicing endonuclease subunit Sen54
Swissprots Q86WV3 Q7Z6J9 Q8N9H2 Q86XE4
Accessions Q7Z6J9 AK094466 BAC04362 AK097583 BAG53490 BC045551 BC047793 AAH47793 BC053643 AAH53643 BE247638 BE251582 BX424294 CV810347 XM_005257229 XP_005257286 XM_006721821 XP_006721884 XM_011524616 XP_011522918 XM_011524617 XP_011522919 XM_011524618 XP_011522920 XR_243646 NM_207346 NP_997229
Function Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. {ECO:0000269|PubMed:15109492}.
Subcellular Location Nucleus {ECO:0000305}. Nucleus, nucleolus {ECO:0000305}. Note=May be transiently localized in the nucleolus. {ECO:0000305}.

TSEN54 (C-1) - sc-374488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TSEN54 (C-1): sc-374488. Western blot analysis of TSEN54 expression in Y79 (A) and Jurkat (B) whole cell lysates.

TSEN54 (H-132) - sc-292014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TSEN54 (H-132): sc-292014. Western blot analysis of TSEN54 expression in non-transfected 293T: sc-117752 (A), human TSEN54 transfected 293T: sc-116179 (B), ARPE-19 (C) and Jurkat (D) whole cell lysates.

TSEN54 (A-9) - sc-398327 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TSEN54 (A-9): sc-398327. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.

TSEN54 (T-15) - sc-165801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TSEN54 (T-15): sc-165801. Western blot analysis of TSEN54 expression in non-transfected: sc-117752 (A) and human TSEN54 transfected: sc-116179 (B) 293T whole cell lysates.

TSEN54 (V-14) - sc-165802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TSEN54 antibody - ab110723 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TSEN54 antibody (ab110723) at 1/500 dilutionLane 1 : 3T3 cell lysateLane 2 : Jurkat cell lysateLane 3 : Jurkat cell lysate with blocking peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-TSEN54 antibody - ab194548 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-TSEN54 antibody (ab194548) at 1/500 dilution + Y-79 cell lysate at 50 µg

Anti-TSEN54 antibody [EPR10062] - ab178696 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10062
All lanes : Anti-TSEN54 antibody [EPR10062] (ab178696) at 1/1000 dilutionLane 1 : MCF7 cell lysateLane 2 : 293T cell lysateLane 3 : Y79 cell lysateLysates/proteins at 10 µg per lane.

Anti-TSEN54 Antibody (aa261-310) - LS-C291414 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TSEN54 Antibody - NBP2-30377 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TSEN54 Antibody [NBP2-30377] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

TSEN54 Antibody - H00283989-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
TSEN54 polyclonal antibody (A01), Lot # 060703JCS1 Western Blot analysis of TSEN54 expression in Y-79 ( Cat # L042V1 ).

Anti-TSEN54 antibody produced in rabbit - HPA053097 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TSEN54: <B>Cat. No. HPA053097</B>: Immunohistochemical staining of human kidney shows moderate positivity in renal tubules.

Anti-TSEN54 antibody produced in rabbit - SAB4300944 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TSEN54: <B>Cat. No. SAB4300944</B>: Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue using Anti-TSEN54 antibody.

TSEN54 Antibody (OAAF04395) - OAAF04395 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TSEN54 Antibody - abx014965 from Abbexa

Host Rabbit
Clonality Polyclonal

TSEN54 / SEN54 antibody - H00283989-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
TSEN54 polyclonal antibody (A01), Lot # 060703JCS1 Western Blot analysis of TSEN54 expression in Y-79 ( Cat # L042V1 ).

Anti-TSEN54 antibody - STJ96124 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

TSEN54 antibody - 14320-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

TSEN54 Polyclonal Antibody - PA003627-C19290 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TSEN54 Antibody - 35110 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 3T3 cells and Jurkat cells, using TSEN54 antibody #35110.

TSEN54 Antibody - E11-19290C from Enogene

Prices $225.00
Sizes 100 μg
Host Rabbit

TSEN54 Antibody - C19290 from Assay Biotechnology

Prices $175.00, $275.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TSEN54 (aa 427-525) polyclonal antibody - DPAB-DC1423 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-TSEN54 (internal region) polyclonal antibody - DPABH-00464 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

TSEN54 Antibody - CSB-PA272793 from Cusabio

Host Rabbit
Clonality Polyclonal
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