Acd

Gene Symbol Acd
Entrez Gene 497652
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description adrenocortical dysplasia
Other Description adrenocortical dysplasia protein
Swissprots Q99KF8 Q3V3Y1 Q3TUR7 Q5EE38 Q3TBB1 Q3UKL6
Accessions AAW82804 EDL11302 EDL11303 Q5EE38 AK032683 BAE43282 AK052768 AK145959 BAE26785 AK160599 BAE35904 AK170606 AK171345 BAE42403 AK171458 BC004682 AAH04682 BC138694 AAI38695 BC138695 AAI38696 BC145384 XM_006531169 XP_006531232 XM_006531170 XP_006531233 XM_006531174 XP_006531237 XM_006531175 XP_006531238 XM_006531176 XP_006531239 XM_011248435 XP_011246737 XR_878844 NM_001012638 NP_001012656
Function Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity (By similarity). Plays a role in shelterin complex assembly. May play an essential role in organogenesis of the developing embryo. {ECO:0000250, ECO:0000269|PubMed:15537664}.
Subcellular Location Nucleus {ECO:0000250}. Chromosome, telomere {ECO:0000305}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15537664}.

Mouse Acd ORF Clone(NM_001012638.1) - CDCL210536 from Creative Biomart

Species Mouse
Accession NM_001012638.1

Mouse Acd ORF Clone(NM_001012638.1) - CDCL210537 from Creative Biomart

Species Mouse
Accession NM_001012638.1

Mouse ACD ORF clone(NM_001012638.1) - CDCH014724 from Creative Biomart

Species Mouse
Accession NM_001012638.1

Mouse ACD Gene cDNA Clone (full-length ORF Clone) - MG51470-G from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, N-Flag tag - MG51470-NF from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, C-Myc tag - MG51470-CM from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - MG51470-CY from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, C-OFPSpark tag - MG51470-ACR from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, N-OFPSpark tag - MG51470-ANR from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, C-GFPSpark tag - MG51470-ACG from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - MG51470-UT from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, N-HA tag - MG51470-NY from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, C-His tag - MG51470-CH from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse ACD natural ORF mammalian expression plasmid, N-GFPSpark tag - MG51470-ANG from Sino Biological

Species Mouse
Accession NM_001012638.1

Mouse Acd ORF clone (NM_001012638.1) - CDCR023692 from Creative biogene

Species Mouse
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