| Gene Symbol |
NXN
|
| Entrez Gene |
64359
|
| Alt Symbol |
NRX, TRG-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nucleoredoxin
|
| Other Description |
nucleoredoxin 1
|
| Swissprots |
D3DTH2 Q9H9Q1 Q6P3U6 Q3SWW6 Q7L4C6 B4DXQ0 Q6DKJ4
|
| Accessions |
EAW90639 EAW90640 EAW90641 Q6DKJ4 AF086523 AK022676 BAB14171 AK027451 BAB55122 AK297990 BAG60298 AK302073 BAG63462 AW752727 AY189690 AAO85223 BC009327 AAH09327 BC063828 AAH63828 BC073845 AAH73845 BC104634 AAI04635 BC152722 AAI52723 BC153025 AAI53026 BU856030 CX786695 XM_005256756 XP_005256813 XM_005256757 XP_005256814 XM_005256758 XP_005256815 NM_001205319 NP_001192248 NM_022463 NP_071908
|
| Function |
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.
|