NXN

Gene Symbol	NXN
Entrez Gene	64359
Alt Symbol	NRX, TRG-4
Species	Human
Gene Type	protein-coding
Description	nucleoredoxin
Other Description	nucleoredoxin 1
Swissprots	D3DTH2 Q9H9Q1 Q6P3U6 Q3SWW6 Q7L4C6 B4DXQ0 Q6DKJ4
Accessions	EAW90639 EAW90640 EAW90641 Q6DKJ4 AF086523 AK022676 BAB14171 AK027451 BAB55122 AK297990 BAG60298 AK302073 BAG63462 AW752727 AY189690 AAO85223 BC009327 AAH09327 BC063828 AAH63828 BC073845 AAH73845 BC104634 AAI04635 BC152722 AAI52723 BC153025 AAI53026 BU856030 CX786695 XM_005256756 XP_005256813 XM_005256757 XP_005256814 XM_005256758 XP_005256815 NM_001205319 NP_001192248 NM_022463 NP_071908
Function	Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.

Nucleoredoxin (E-12) - sc-393748 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Nucleoredoxin (E-12): sc-393748. Western blot analysis of Nucleoredoxin expression in HeLa whole cell lysate (A) and human heart (B) and human liver (C) tissue extracts.

Nucleoredoxin (D-14) - sc-161973 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Nucleoredoxin (D-14): sc-161973. Western blot analysis of Nucleoredoxin expression in HeLa (A), K-562 (B), HEK293 (C), Hep G2 (D) and THP-1 (E) whole cell lysates.

Nucleoredoxin (H-65) - sc-368660 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Anti-NXN [EPR15177] antibody - ab191429 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR15177

All lanes : Anti-NXN [EPR15177] antibody (ab191429) at 1/10000 dilutionLane 1 : 293 lysateLane 2 : HepG2 lysateLane 3 : HeLa lysateLane 4 : SH-SY5Y lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Anti-NXN antibody - ab113017 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN antibody (ab113017) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

Anti-NXN antibody - ab69063 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-NXN antibody (ab69063) at 1/500 dilution + Human kidney tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-NXN antibody - ab88753 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-NXN antibody (ab88753) at 1 µg/ml + Human kidney tissue lysate at 50ug/lane

Anti-NXN Antibody (aa221-249) - LS-C163085 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

NXN Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-NXN Antibody (aa131-435) - LS-C126003 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, APC) - LS-C246678 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, Azide-free, HRP) - LS-C248964 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, Biotin) - LS-C246679 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, PE) - LS-C246681 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, AP) - LS-C246677 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa221-249, FITC) - LS-C246680 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa167-435, Biotin) - LS-C297650 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa166-327, Biotin) - LS-C298618 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa220-249) - LS-C323497 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa167-435, FITC) - LS-C303169 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa166-327, FITC) - LS-C305204 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa90-139) - LS-C145653 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

NXN antibody LS-C145653 Western blot of H226 Cell lysate. Antibody concentration 1 ug/ml.

Anti-NXN Antibody (aa166-327) - LS-C295703 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NXN Antibody (aa167-435) - LS-C295705 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Nucleoredoxin Antibody - AF5719 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

Western blot shows lysates of HEK293 human embryonic kidney cell line and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Human Nucleoredoxin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5719) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for Nucleoredoxin at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.

Nucleoredoxin Antibody - NBP1-82289 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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