PARPBP

Gene Symbol PARPBP
Entrez Gene 55010
Alt Symbol AROM, C12orf48, PARI
Species Human
Gene Type protein-coding
Description PARP1 binding protein
Other Description PARP-1 binding protein|PARP1-binding protein|PCNA-interacting partner
Swissprots Q9NWS1 Q4KMW7 B4E0Y0 Q05C00 Q4FZA0 Q6NSC6 Q86W36 Q499L8 Q6PJA1
Accessions EAW97690 EAW97691 EAW97692 Q9NWS1 AA757264 AF274940 AAK07517 AK000648 BAA91306 AK300041 BAG61852 AK302724 BAG63943 AK303571 BAG64592 BC014313 BC018903 AAH18903 BC030962 AAH30962 BC050696 AAH50696 BC070270 AAH70270 BC098297 BC098313 AAH98313 BC099734 AAH99734 BC099844 AAH99844 DB260405 XM_011538506 XP_011536808 XM_011538507 XP_011536809 XM_011538508 XP_011536810 XM_011538509 XP_011536811 XM_011538510 XP_011536812 XM_011538511 XP_011536813 XM_011538512 XP_011536814 XM_011538513 XP_011536815 XM_011538514 XP_011536816 XM_011538515 XP_011536817 XM_011538516 XP_011536818 XM_011538517 XP_011536819 XM_011538518 XP_011536820 XM_011538519 XP_011536821 XM_011538520 XP_011536822 NM_017915 NP_060385
Function Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP- ribosyl)ation activity of PARP1; however such function may be indirect. {ECO:0000269|PubMed:20931645, ECO:0000269|PubMed:22153967}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20931645, ECO:0000269|PubMed:22153967}. Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA.
Tissue Specificity Restricted to testis. Overexpressed in multiple cancer cells. {ECO:0000269|PubMed:20931645}.

PARPBP / C12orf48 Antibody Blocking Peptide - LS-E36 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PARPBP / C12orf48 Antibody Blocking Peptide - LS-E24532 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

C12orf48-Antibody-C-term-Blocking-peptide - BP10083b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human PCNA-interacting partner(PARPBP) - CSB-YP868339HU CSB-EP868339HU CSB-BP868339HU CSB-MP868339HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Protein AroM(aroM) - CSB-YP365077SZB CSB-EP365077SZB CSB-BP365077SZB CSB-MP365077SZB from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Shigella

PCNA-interacting partner (PARPBP), Recombinant Protein - MBS1403509 from MyBioSource

Category Protein
Prices $1,380.00, $1,380.00, $1,595.00, $1,595.00, $2,295.00, $2,295.00, $2,760.00, $2,760.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Protein AroM (aroM), Recombinant Protein - MBS1187586 from MyBioSource

Category Protein
Prices $975.00, $975.00, $1,200.00, $1,200.00, $1,475.00, $1,475.00, $1,940.00, $1,940.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Shigella

C12orf48 Recombinant Protein Antigen - NBP1-93969PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PARPBP Peptide, Human - M34GP11325H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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