Gene Symbol | SUDS3 |
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Entrez Gene | 64426 |
Alt Symbol | SAP45, SDS3 |
Species | Human |
Gene Type | protein-coding |
Description | suppressor of defective silencing 3 homolog (S. cerevisiae) |
Other Description | 45 kDa Sin3-associated polypeptide|sin3 histone deacetylase corepressor complex component SDS3|sin3A-associated protein, 45kDa|suppressor of defective silencing 3 protein homolog |
Swissprots | Q9H8D2 Q4KMQ5 Q9H7L9 Q8N6H0 |
Accessions | EAW98137 EAW98138 EAW98139 EAW98140 EAW98141 Q9H7L9 AA916093 AK023801 BAB14685 AK024460 BAB15750 AK026749 BC030252 AAH30252 BC045728 BC093990 AAH93990 BC098404 AAH98404 BC112000 AAI12001 BX647687 XM_011538671 XP_011536973 XM_011538672 XP_011536974 XM_011538673 XP_011536975 XM_011538674 XP_011536976 XR_944677 NM_022491 NP_071936 |
Function | Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. {ECO:0000269|PubMed:12724404, ECO:0000269|PubMed:21239494}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21239494}. |
Tissue Specificity | Expressed in various cancer cell ines. {ECO:0000269|PubMed:12724404}. |
SDS3 (C-12) - sc-109430 from Santa Cruz Biotechnology
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SDS3 (P-16) - sc-109431 from Santa Cruz Biotechnology
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Anti-SDS3 antibody - ab3740 from Abcam
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Anti-SDS3 antibody - ab89345 from Abcam
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Anti-SDS3 antibody [EPR15000] - ab184555 from Abcam
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Anti-SDS3 antibody - N-terminal - ab177453 from Abcam
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Anti-SUDS3 Antibody - LS-C91260 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa150-200) - LS-C91261 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, APC) - LS-C270656 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, AP) - LS-C270655 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, Biotin) - LS-C270657 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, FITC) - LS-C270658 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, PE) - LS-C270660 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98, Azide-free, HRP) - LS-C270659 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa150-200) - LS-C288555 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98) - LS-C325487 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (N-Terminus) - LS-C186717 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa175-225) - LS-C287151 from LifeSpan Bioscience
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Anti-SUDS3 Antibody (aa71-98) - LS-C157111 from LifeSpan Bioscience
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SDS3 Antibody - NB100-257 from Novus Biologicals
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SDS3 Antibody - NB100-93318 from Novus Biologicals
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SDS3 Antibody - H00064426-B01 from Novus Biologicals
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SDS3 Antibody - H00064426-B01P from Novus Biologicals
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Anti-SUDS3 antibody produced in rabbit - HPA041972 from Sigma-Aldrich
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Anti-SUDS3 (187-200) antibody produced in rabbit - SAB1105118 from Sigma-Aldrich
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