GPM6A

Gene Symbol GPM6A
Entrez Gene 2823
Alt Symbol GPM6, M6A
Species Human
Gene Type protein-coding
Description glycoprotein M6A
Other Description neuronal membrane glycoprotein M6-a
Swissprots Q92602 B7Z642 E9PHI5 P51674
Accessions EAX04724 EAX04725 P51674 AI609188 AK226176 AK299788 BAH13128 AX772804 CAE06251 BC010461 BC022508 AAH22508 BC022528 AAH22528 BC032904 BC037853 AAH37853 BC044612 AAH44612 BC053954 BI544825 BI546539 BI596896 BI670059 D49958 BAA08712 DA190376 DA196860 DA507772 DA528125 DA621566 DA915764 DC353381 DQ892372 ABM83298 DQ895581 ABM86507 H16369 U45956 AAB16889 XM_006714183 XP_006714246 XM_011531877 XP_011530179 NM_001261447 NP_001248376 NM_001261448 NP_001248377 NM_005277 NP_005268 NM_201591 NP_963885 NM_201592 NP_963886 NR_048571
Function Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. {ECO:0000269|PubMed:19298174}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons (By similarity). {ECO:0000250}.

M6A (T-14) - sc-168523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Neuronal membrane glycoprotein M6-a antibody - ab79128 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Neuronal membrane glycoprotein M6-a antibody (ab79128) at 1 µg/mlLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : Brain (Human) Membrane Lysate - adult normal tissue (ab29456)Lane 3 : Brain (Mouse) Tissue Lysate Lane 4 : Spinal Cord (Mouse) Tissue LysateLane 5 : Brain (Rat) Tissue Lysate Lane 6 : Spinal Cord (Rat) Tissue Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Neuronal membrane glycoprotein M6-a antibody - ab130956 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of Rat hippocampal culture neurons labeling Neuronal membrane glycoprotein M6-a (green) with ab130956 at 1:250. An AlexaFluor®488-conjugated anti-rabbit IgG (1/1000) was used as the secondary antibody. Blue - nucleus (DAPI).

Anti-Neuronal membrane glycoprotein M6-a antibody - ab109997 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Neuronal membrane glycoprotein M6-a antibody (ab109997) at 0.5 µg/ml + Rat Brain lysate at 35 µg

Anti-Neuronal membrane glycoprotein M6-a antibody - ab102642 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Neuronal membrane glycoprotein M6-a antibody (ab102642) at 1/100 dilution + Mouse brain tissue lysate at 35 µg

Anti-Neuronal membrane glycoprotein M6-a antibody - C-terminal - ab171306 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human stomach tissue labeling Neuronal membrane glycoprotein M6-a using ab171306 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-GPM6A / Glycoprotein M6A Antibody (aa232-259) IHC-plus™ - LS-B12079 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, Biotin) - LS-C257942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, FITC) - LS-C259567 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, APC) - LS-C257940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, AP) - LS-C257939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, Azide-free, HRP) - LS-C259568 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275, PE) - LS-C259569 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, AP) - LS-C259570 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, APC) - LS-C259571 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, FITC) - LS-C259572 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, Azide-free, HRP) - LS-C259573 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, Biotin) - LS-C259574 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268, PE) - LS-C259575 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa253-278) - LS-C321726 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa238-268) - LS-C321728 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPM6A / Glycoprotein M6A Antibody (aa246-275) - LS-C166613 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GPM6A Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GPM6A / Glycoprotein M6A Antibody (aa59-70) IHC-plus™ - LS-B9226 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GPM6A / M6A antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPM6A / Glycoprotein M6A Antibody (C-Terminus) IHC-plus™ - LS-B12039 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-GPM6A / Glycoprotein M6A Antibody (C-Terminus) IHC-plus™ - LS-B12040 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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