Gprc6a

Gene Symbol Gprc6a
Entrez Gene 210198
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description G protein-coupled receptor, family C, group 6, member A
Other Description G-protein coupled receptor family C group 6 member A
Swissprots Q5DK52 Q5DK51 Q8K4Z6
Accessions EDL05066 Q8K4Z6 AY101365 AAM22280 AY735399 AAW68012 AY735400 AAW68013 AY735401 AAW68014 BC108998 AAI08999 XM_011243151 XP_011241453 NM_153071 NP_694711
Function Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids. {ECO:0000269|PubMed:15576628, ECO:0000269|PubMed:16199532, ECO:0000269|PubMed:19050760, ECO:0000269|PubMed:20947496}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15816861}; Multi-pass membrane protein {ECO:0000269|PubMed:15816861}.
Tissue Specificity Expressed at high level in liver, lung, spleen and heart. Expressed at lower level in kidney, skeletal muscle and brain. Expressed in E7, E11, E15 and E17 embryos. {ECO:0000269|PubMed:15816861, ECO:0000269|PubMed:16199532}.

Mouse GPRC6A ORF clone(NM_153071.1) - CDCG010053 from Creative Biomart

Species Mouse
Accession NM_153071.1

Mouse Gprc6a ORF Clone(NM_153071.1) - CDCL165289 from Creative Biomart

Species Mouse
Accession NM_153071.1

Mouse Gprc6a ORF Clone(NM_153071.1) - CDCR270075 from Creative Biomart

Species Mouse
Accession NM_153071.1

Mouse Gprc6a ORF Clone(NM_153071.1) - CDCR270076 from Creative Biomart

Species Mouse
Accession NM_153071.1

Human Gprc6a ORF clone (NM_153071.1) - CDCL114355 from Creative biogene

Species Mouse
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