Gprc6a

Gene Symbol Gprc6a
Entrez Gene 210198
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description G protein-coupled receptor, family C, group 6, member A
Other Description G-protein coupled receptor family C group 6 member A
Swissprots Q5DK52 Q5DK51 Q8K4Z6
Accessions EDL05066 Q8K4Z6 AY101365 AAM22280 AY735399 AAW68012 AY735400 AAW68013 AY735401 AAW68014 BC108998 AAI08999 XM_011243151 XP_011241453 NM_153071 NP_694711
Function Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids. {ECO:0000269|PubMed:15576628, ECO:0000269|PubMed:16199532, ECO:0000269|PubMed:19050760, ECO:0000269|PubMed:20947496}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15816861}; Multi-pass membrane protein {ECO:0000269|PubMed:15816861}.
Tissue Specificity Expressed at high level in liver, lung, spleen and heart. Expressed at lower level in kidney, skeletal muscle and brain. Expressed in E7, E11, E15 and E17 embryos. {ECO:0000269|PubMed:15816861, ECO:0000269|PubMed:16199532}.

GPRC6A CRISPR/Cas9 KO Plasmid (m) - sc-431685 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A HDR Plasmid (m) - sc-431685-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A Double Nickase Plasmid (m) - sc-431685-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A Double Nickase Plasmid (m2) - sc-431685-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A CRISPR Activation Plasmid (m) - sc-431685-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A CRISPR Activation Plasmid (m2) - sc-431685-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A Lentiviral Activation Particles (m) - sc-431685-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A Lentiviral Activation Particles (m2) - sc-431685-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GPRC6A siRNA (m) - sc-62414 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GPRC6A shRNA Plasmid (m) - sc-62414-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GPRC6A shRNA (m) Lentiviral Particles - sc-62414-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN32790 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32790 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GPRC6A siRNA (Mouse) - CRN1681 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GPRC6A - MBS8239325 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Gprc6a (NM_153071.1) - SHH307238 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Gprc6a(NM_153071.1) - SHH101675 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse GPRC6A siRNA - orb291156 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GPRC6A shRNA Plasmid (Mouse) - CHN1681 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

GPRC6A miRNA 3'UTR clone - MiUTR1M-05336 from Creative biogene

Species Reactivities Mouse
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