Gene Symbol | ILF3 |
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Entrez Gene | 3609 |
Alt Symbol | CBTF, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF110, NF110b, NF90, NF90a, NF90b, NFAR, NFAR-1, NFAR2, TCP110, TCP80 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin enhancer binding factor 3, 90kDa |
Other Description | M-phase phosphoprotein 4|double-stranded RNA-binding protein, 76 kD|dsRNA binding protein NFAR-2/MPP4|interleukin enhancer binding factor 3, 90kD|interleukin enhancer-binding factor 3|nuclear factor associated with dsRNA|nuclear factor of activated T-cells 90 kDa|nuclear factor of activated T-cells, 90 kD|translational control protein 80 |
Swissprots | Q9NRN2 Q9NQ98 Q9NQ99 A8K6F2 Q9NQA0 Q9NQA2 G5E9M5 Q9NRN4 Q9NQA1 Q9UMZ9 Q9BZH4 Q9NRN3 Q9NQ95 Q9BZH5 Q9UNA2 Q9NQ96 O43409 Q9UN84 Q9UN00 Q6P1X1 Q99544 Q99545 Q12906 Q9NQ97 Q86XY7 |
Accessions | AAF82685 AAF82686 AAF82687 AAK07424 AAK07425 CAC01121 CAC01122 CAC01123 CAC01124 EAW84131 EAW84132 EAW84133 EAW84134 EAW84135 EAW84136 EAW84137 Q12906 AB209062 BAD92299 AF007140 AAC19152 AF141870 AAD37575 AF147209 AAD33966 AF167569 AAD51098 AF167570 AAD51099 AJ271744 CAC01404 AJ271745 CAC01405 AJ271746 CAC01406 AK000018 BAA90887 AK023222 AK025821 BAB15245 AK291205 BAF83894 AK291617 BAF84306 AK293170 BAG56714 AK294084 BAG57425 AL832528 AW576353 AY240961 AAP68989 BC001770 BC003086 BC014221 BC018633 BC048314 AAH48314 BC064836 AAH64836 BM973331 CR457223 CAG33504 DC320902 HQ322263 AEE02018 HQ322264 AEE02019 HQ322265 AEE02020 U10324 AAA20994 X98264 CAA66917 X98265 CAA66918 XM_005259895 XP_005259952 XM_006722742 XP_006722805 XM_011527984 XP_011526286 XM_011527985 XP_011526287 XM_011527986 XP_011526288 XM_011527987 XP_011526289 NM_001137673 NP_001131145 NM_004516 NP_004507 NM_012218 NP_036350 NM_017620 NP_060090 NM_153464 NP_703194 |
Function | May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N- methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. The phosphorylated form at Thr-188 and Thr-315, in concert with EIF2AK2/PKR can inhibit vesicular stomatitis virus (VSV) replication (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in response to viral dsRNA. The unphosphorylated form is retained in the nucleus by ILF2. Phosphorylation at Thr-188 and Thr-315 causes the dissociation of ILF2 from the ILF2-ILF3 complex resulting in a cytoplasmic sequestration of ILF3. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
Tissue Specificity | Ubiquitous. |
Interleukin enhancer-binding factor 3 (ILF3), Human, ELISA Kit - CSB-EL011684HU from ARP American Research Products
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Interleukin enhancer-binding factor 3, ILF3, Human, ELISA Kit - E2285h from ARP American Research Products
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ILF3 (Human) IP-WB Antibody Pair - H00003609-PW1 from Acris Antibodies
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Human MMP4 ELISA Kit - HM0316 from NeoScientific
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Anserine MMP4 ELISA Kit - AM0316 from NeoScientific
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Interleukin enhancer-binding factor 3 (ILF3), ELISA Kit - MBS925724 from MyBioSource
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Human Interleukin enhancer-binding factor 3(ILF3) ELISA kit - CSB-EL011684HU from Cusabio
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Human Matrix Metalloproteinase 4 ELISA - E01M0309 from BlueGene Biotech
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Human NF90 / ILF3 ELISA Kit (Sandwich ELISA) - LS-F19676 from LifeSpan Bioscience
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Mouse NF90 / ILF3 ELISA Kit (Sandwich ELISA) - LS-F19675 from LifeSpan Bioscience
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Rat NF90 / ILF3 ELISA Kit (Custom ELISA) - LS-F19677 from LifeSpan Bioscience
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Human Interleukin enhancer-binding factor 3 ELISA Kit - abx251543 from Abbexa
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Human Interleukin enhancer-binding factor 3 (ILF3) ELISA Kit - EKC34256 from Biomatik
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Human Interleukin enhancer-binding factor 3 ELISA Kit - EKE52451 from Biomatik
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ILF3 - EKH4402 from Nordic BioSite
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Human ILF3 ELISA Kit - E020812 from Biobool
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Human MMP4 ELISA Kit - E023803 from Biobool
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Human MMP-4 ELISA Kit - E024240 from Biobool
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ILF3 ELISA Kit (Human) (OKEH05183) - OKEH05183 from Aviva Systems Biology
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Human MMP4 ELISA Kit - EHM0316 from ABclonal
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Interleukin enhancer-binding factor 3, ELISA Kit - MBS2886118 from MyBioSource
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Human NF90 / ILF3 ELISA Kit (Sandwich ELISA) - LS-F33519 from LifeSpan Bioscience
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