ILF3

Gene Symbol ILF3
Entrez Gene 3609
Alt Symbol CBTF, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF110, NF110b, NF90, NF90a, NF90b, NFAR, NFAR-1, NFAR2, TCP110, TCP80
Species Human
Gene Type protein-coding
Description interleukin enhancer binding factor 3, 90kDa
Other Description M-phase phosphoprotein 4|double-stranded RNA-binding protein, 76 kD|dsRNA binding protein NFAR-2/MPP4|interleukin enhancer binding factor 3, 90kD|interleukin enhancer-binding factor 3|nuclear factor associated with dsRNA|nuclear factor of activated T-cells 90 kDa|nuclear factor of activated T-cells, 90 kD|translational control protein 80
Swissprots Q9NRN2 Q9NQ98 Q9NQ99 A8K6F2 Q9NQA0 Q9NQA2 G5E9M5 Q9NRN4 Q9NQA1 Q9UMZ9 Q9BZH4 Q9NRN3 Q9NQ95 Q9BZH5 Q9UNA2 Q9NQ96 O43409 Q9UN84 Q9UN00 Q6P1X1 Q99544 Q99545 Q12906 Q9NQ97 Q86XY7
Accessions AAF82685 AAF82686 AAF82687 AAK07424 AAK07425 CAC01121 CAC01122 CAC01123 CAC01124 EAW84131 EAW84132 EAW84133 EAW84134 EAW84135 EAW84136 EAW84137 Q12906 AB209062 BAD92299 AF007140 AAC19152 AF141870 AAD37575 AF147209 AAD33966 AF167569 AAD51098 AF167570 AAD51099 AJ271744 CAC01404 AJ271745 CAC01405 AJ271746 CAC01406 AK000018 BAA90887 AK023222 AK025821 BAB15245 AK291205 BAF83894 AK291617 BAF84306 AK293170 BAG56714 AK294084 BAG57425 AL832528 AW576353 AY240961 AAP68989 BC001770 BC003086 BC014221 BC018633 BC048314 AAH48314 BC064836 AAH64836 BM973331 CR457223 CAG33504 DC320902 HQ322263 AEE02018 HQ322264 AEE02019 HQ322265 AEE02020 U10324 AAA20994 X98264 CAA66917 X98265 CAA66918 XM_005259895 XP_005259952 XM_006722742 XP_006722805 XM_011527984 XP_011526286 XM_011527985 XP_011526287 XM_011527986 XP_011526288 XM_011527987 XP_011526289 NM_001137673 NP_001131145 NM_004516 NP_004507 NM_012218 NP_036350 NM_017620 NP_060090 NM_153464 NP_703194
Function May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N- methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. The phosphorylated form at Thr-188 and Thr-315, in concert with EIF2AK2/PKR can inhibit vesicular stomatitis virus (VSV) replication (By similarity). {ECO:0000250}.
Subcellular Location Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in response to viral dsRNA. The unphosphorylated form is retained in the nucleus by ILF2. Phosphorylation at Thr-188 and Thr-315 causes the dissociation of ILF2 from the ILF2-ILF3 complex resulting in a cytoplasmic sequestration of ILF3. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue Specificity Ubiquitous.

NF90 CRISPR/Cas9 KO Plasmid (h) - sc-402626 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 HDR Plasmid (h) - sc-402626-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 Double Nickase Plasmid (h) - sc-402626-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 Double Nickase Plasmid (h2) - sc-402626-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 CRISPR Activation Plasmid (h) - sc-402626-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 CRISPR Activation Plasmid (h2) - sc-402626-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 Lentiviral Activation Particles (h) - sc-402626-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 Lentiviral Activation Particles (h2) - sc-402626-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NF90 siRNA (h) - sc-106301 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NF90 shRNA Plasmid (h) - sc-106301-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NF90 shRNA (h) Lentiviral Particles - sc-106301-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ILF3 RNAi - H00003609-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ILF3 RNAi - H00003609-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU084971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10647 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10647 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13862 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13862

ILF3 siRNA (Human) - CRH2416 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ILF3 RNAi - H00003609-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ILF3 - MBS8220162 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ILF3 (NM_004516.3) - SHH319185 from Creative biogene

Category siRNA
Species Reactivities Human

Human ILF3 siRNA - orb262918 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ILF3 shRNA Plasmid (Human) - CHH2416 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ILF3 miRNA 3'UTR clone - MiUTR3H-05746 from Creative biogene

Species Reactivities Human

ILF3 miRNA 3'UTR clone - MiUTR3H-05747 from Creative biogene

Species Reactivities Human
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