EFNA4

Gene Symbol	EFNA4
Entrez Gene	1945
Alt Symbol	EFL4, EPLG4, LERK4
Species	Human
Gene Type	protein-coding
Description	ephrin-A4
Other Description	LERK-4|eph-related receptor tyrosine kinase ligand 4|ligand of eph-related kinase 4
Swissprots	C9JHJ8 Q6FI57 O95457 Q5SR71 G3XAK2 P52798
Accessions	CAC48189 EAW53138 EAW53139 EAW53140 P52798 AI459151 AI625552 AJ006352 CAA06992 AJ006353 CAA06993 BC042610 BC107483 AAI07484 BE780161 BM740848 BM747625 BQ940212 CD671399 CR533569 CAG38600 U14188 AAC50079 NM_005227 NP_005218 NM_182689 NP_872631 NM_182690 NP_872632
Function	Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Subcellular Location	Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor.
Tissue Specificity	Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.
Top Pathways	Axon guidance, PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Ephrin A4 protein fragment - ab191954 from Abcam Category Protein Source HEK 293 cells Species Mouse

EFNA4-Antibody-Center-Blocking-Peptide - BP8835c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Ephrin-A4 Fc Chimera, CF - 369-EA-200 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Mouse Ephrin-A4 Fc Chimera, CF - 569-A4-200 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human Ephrin-A4 Fc Chimera Biotinylated Protein - BT369 from R&D Systems Category Protein Prices $259.00 Sizes 25 µg Source Mouse myeloma cell line, NS0-derived Human Ephrin-A4 (Leu26 - Gly171) Accession # P52798 IEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus Species Human

Recombinant Mouse Ephrin-A4 Fc Chimera Biotinylated Protein - BT569 from R&D Systems Category Protein Prices $259.00 Sizes 25 µg Source Mouse myeloma cell line, NS0-derived Human Ephrin-A4 (Leu26 - Gly176) Accession # Q3UQB5 DIEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Mouse

Ephrin A4 Protein (OPPA01391) - OPPA01391 from Aviva Systems Biology Category Protein Prices $315.00 Sizes 2 µg Source E. Coli

Ephrin-A4 protein - orb171572 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 200 μg, 500 μg Source Human Cells Species Human

EFNA4 Blocking Peptide - 33R-3471 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Ephrin A4 Recombinant Protein - 96-251 from ProSci Category Protein Prices $350.00 Sizes 250 µg Source HEK293 cells Species Human

Ephrin A4 Recombinant Protein - 96-250 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

EFNA4 fusion protein - ag16105 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

EFNA4 fusion protein - ag15664 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Ephrin A4 Human - PRPS-505 from NeoScientific Category Protein Prices $351.00, $637.00 Sizes 5 µg, 10 µg Source Escherichia Coli. Species Human

Recombinant Human Ephrin A4 Protein - BP001952-PRO-498 from Syd Labs Category Protein Prices $175.00, $270.00, $490.00 Sizes 2 µg, 5 µg, 10 µg Source E. coli-derived. Species Human

Ephrin-A4 - GWB-2392BC from Genway Biotech Category Protein Prices $438.00 Sizes 10 µg

Recombinant Human Ephrin-A4 - EFNA4-151H from Creative Biomart Category Protein Source Recombinant Human full length Ephrin A1 protein expressed in E.coli .

Recombinant Human Ephrin-A4 - EFNA4-1610H from Creative Biomart Category Protein Source NSO cells.

Recombinant Human EFNA4, Fc-tagged - EFNA4-275H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human EFNA4, Fc-tagged - EFNA4-177H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human Ephrin-A4, GST-Tagged - EFNA4-4336H from Creative Biomart Category Protein Source Human

Ephrin A4 Human - NKX-964 from Reagent Proteins Category Protein Prices $421.00, $530.00, $758.00 Sizes 2.00 µg, 5.00 µg, 10.00 µg Source E.coli Species Human

Recombinant Ephrin A4 (EFNA4) - RPE110Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Ephrin A4 (EFNA4) - RPE110Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Ephrin A4 (EFNA4) - RPE110Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

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