CALR

Gene Symbol CALR
Entrez Gene 811
Alt Symbol CRT, HEL-S-99n, RO, SSA, cC1qR
Species Human
Gene Type protein-coding
Description calreticulin
Other Description CRP55|ERp60|HACBP|Sicca syndrome antigen A (autoantigen Ro; calreticulin)|calregulin|endoplasmic reticulum resident protein 60|epididymis secretory sperm binding protein Li 99n|grp60
Swissprots Q9UDG2 Q6IAT4 P27797
Accessions AAB51176 CAK18761 CCD35250 CRH09108 EAW84330 EAW84331 EAW84332 P27797 AB451408 BAG70222 AF087986 AK130190 AK223060 BAD96780 AK295230 BAG58223 AK304492 BAG65301 AY047586 AAL13126 BC002500 AAH02500 BC007911 AAH07911 BC020493 AAH20493 BC107102 BT007448 AAP36116 CR457070 CAG33351 FJ224311 ACI46003 M32294 AAA36582 M84739 AAA51916 NM_004343 NP_004334
Function Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen {ECO:0000250}. Note=Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.
Top Pathways Chagas disease (American trypanosomiasis), Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Antigen processing and presentation

Calregulin CRISPR/Cas9 KO Plasmid (h) - sc-400775 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin HDR Plasmid (h) - sc-400775-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin Double Nickase Plasmid (h) - sc-400775-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin Double Nickase Plasmid (h2) - sc-400775-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin CRISPR Activation Plasmid (h) - sc-400775-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin CRISPR Activation Plasmid (h2) - sc-400775-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin Lentiviral Activation Particles (h) - sc-400775-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin Lentiviral Activation Particles (h2) - sc-400775-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin siRNA (h) - sc-29234 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calregulin shRNA Plasmid (h) - sc-29234-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calregulin shRNA (h) Lentiviral Particles - sc-29234-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU046961 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5308 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5308 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CALR siRNA (Human) - CRH0566 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Calreticulin RNAi - H00000811-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CALR - MBS8219899 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Calregulin CRISPR/Cas9 KO Plasmid (h2) - sc-400775-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calregulin HDR Plasmid (h2) - sc-400775-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CALR (NM_004343.3) - SHH253897 from Creative biogene

Category siRNA
Species Reactivities Human

Human CALR siRNA - orb261068 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CALR shRNA Plasmid (Human) - CHH0566 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CALR miRNA 3'UTR clone - MiUTR3H-00230 from Creative biogene

Species Reactivities Human
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