CALR

Gene Symbol	CALR
Entrez Gene	811
Alt Symbol	CRT, HEL-S-99n, RO, SSA, cC1qR
Species	Human
Gene Type	protein-coding
Description	calreticulin
Other Description	CRP55|ERp60|HACBP|Sicca syndrome antigen A (autoantigen Ro; calreticulin)|calregulin|endoplasmic reticulum resident protein 60|epididymis secretory sperm binding protein Li 99n|grp60
Swissprots	Q9UDG2 Q6IAT4 P27797
Accessions	AAB51176 CAK18761 CCD35250 CRH09108 EAW84330 EAW84331 EAW84332 P27797 AB451408 BAG70222 AF087986 AK130190 AK223060 BAD96780 AK295230 BAG58223 AK304492 BAG65301 AY047586 AAL13126 BC002500 AAH02500 BC007911 AAH07911 BC020493 AAH20493 BC107102 BT007448 AAP36116 CR457070 CAG33351 FJ224311 ACI46003 M32294 AAA36582 M84739 AAA51916 NM_004343 NP_004334
Function	Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen {ECO:0000250}. Note=Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.
Top Pathways	Chagas disease (American trypanosomiasis), Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Calreticulin full length protein - ab15729 from Abcam Category Protein Prices $235.00 Sizes 100 µg Source Native

Calreticulin peptide - ab4927 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Calreticulin peptide - ab5838 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human Calreticulin full length protein - ab91577 from Abcam Category Protein Prices $188.00 Sizes 50 µg Source E. coli Species Human

Human Calreticulin peptide - ab39895 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Calreticulin peptide - ab39896 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Calreticulin protein fragment - ab40609 from Abcam Category Protein Prices $235.00 Sizes 50 µg Source E. coli Species Human

CALR / Calreticulin Antibody Blocking Peptide - LS-E10487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALR / Calreticulin Antibody Blocking Peptide - LS-E10488 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALR / Calreticulin Antibody Blocking Peptide - LS-E21547 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALR / Calreticulin Antibody Blocking Peptide - LS-E21267 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CALR / Calreticulin Blocking Peptide - LS-E8533 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Calreticulin Recombinant Protein - H00000811-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Calreticulin Protein - NBP1-44499 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CALR-Antibody-Center-Blocking-Peptide - BP6898c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Calreticulin Recombinant Protein - GTX48222-PRO from GeneTex Category Protein Prices $329.00 Sizes 50 μg Source E. coli Species Human

Recombinant human Calreticulin (OPCA00726) - OPCA00726 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

CALR Protein (OPPA02268) - OPPA02268 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human CALR protein (His Tag) - orb138300 from Biorbyt Category Protein Prices $476.00, $748.00 Sizes 20 μg, 50 μg Source Human Cells Species Human

Human CRT Calreticulin protein - orb245348 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CALR protein - orb80990 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human CALR protein - orb138299 from Biorbyt Category Protein Prices $357.00, $612.00 Sizes 20 μg, 50 μg Source Human Cells Species Human

Calreticulin Blocking Peptide - 33R-10619 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Calreticulin protein (His tag) - 80R-1306 from Fitzgerald Category Protein Prices $395.00 Sizes 100 µg Source E.coli

Calreticulin protein (His tag) - 80R-3194 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

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