MMP19

Gene Symbol MMP19
Entrez Gene 4327
Alt Symbol MMP18, RASI-1
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 19
Other Description matrix metalloproteinase RASI|matrix metalloproteinase-18|matrix metalloproteinase-19|matrix metalloproteinase-beta19
Swissprots Q99580 O15278 O95606 B4E030 Q99542
Accessions AAT97983 EAW96844 EAW96845 Q99542 AK225939 AK297999 BAG60305 AK303202 BAG64292 AL545199 BC030206 BC050368 AAH50368 BI761698 HQ448618 ADQ33096 U37791 AAC51521 U38320 AAB63007 U38321 AAB63008 U38322 AAB63009 U38431 AAC99995 X92521 CAA63299 Y08622 CAA69913 XM_006719401 XP_006719464 XM_011538358 XP_011536660 XM_011538359 XP_011536661 XR_429102 XR_944553 NM_001272101 NP_001259030 NM_002429 NP_002420 NR_073606 NM_001032360 NM_022790 NM_022792
Function Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin. {ECO:0000269|PubMed:10809722, ECO:0000269|PubMed:10922468}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients.

MMP-19 (F-15) - sc-26891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MMP-19 (C-17) - sc-130174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MMP-19 (C-17): sc-130174. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Anti-MMP19 antibody - ab53146 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP19 antibody (ab53146) at 1/500 dilutionLane 1 : Extracts of Huv Ec cells with no peptideLane 2 : Extracts of Huv Ec cells with peptide

Anti-MMP19 antibody - ab89689 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-MMP19 antibody (ab89689) at 1 µg/ml + HeLa cell lysate at 50 µg

Anti-MMP19 antibody - ab38966 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab38966 staining Human normal Liver parenchyma. Staining is localized to the cytoplasm and secreted.Left panel: with primary antibody at 2 ug/ml. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer EDTA pH 9.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS), then incubated with primary antibody for 20 minutes, and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-MMP19 antibody - ab39005 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP19 antibody, prediluted - ab15477 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab15477 staining MMP19 in human placenta by Immunohistochemistry (FFPE-sections).

Anti-MMP19 antibody - Aminoterminal end - ab39002 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab39002 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab39002, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-MMP19 antibody - Carboxyterminal end - ab39029 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP19 rasi6 antibody - ab135563 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast carcinoma tissue labelling MMP19 rasi6 with ab135563 at 1/50 dilution followed by peroxidase-conjugated secondary antibody and AEC staining.

Anti-MMP19 rasi6 antibody - ab154496 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP19 rasi6 antibody (ab154496) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HCT116 whole cell lysateLane 3 : MCF7 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-MMP19 Antibody (aa359-373) - LS-C3128 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody - LS-C8894 from LifeSpan Bioscience

Prices $485.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody - LS-C87091 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (aa54-84, PE) - LS-C223300 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (aa229-508) - LS-C182912 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, AP) - LS-C225821 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, APC) - LS-C225822 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, PE) - LS-C225826 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, Azide-free, HRP) - LS-C225825 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, Biotin) - LS-C225824 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (C-Terminus, FITC) - LS-C225834 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (N-Terminus) IHC-plus™ - LS-B5291 from LifeSpan Bioscience

Prices $395.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
Anti-MMP19 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5291 dilution 1:50.

Anti-MMP19 Antibody (aa54-84, APC) - LS-C226881 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP19 Antibody (aa54-84, Biotin) - LS-C226883 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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