Gene Symbol | MMP19 |
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Entrez Gene | 4327 |
Alt Symbol | MMP18, RASI-1 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 19 |
Other Description | matrix metalloproteinase RASI|matrix metalloproteinase-18|matrix metalloproteinase-19|matrix metalloproteinase-beta19 |
Swissprots | Q99580 O15278 O95606 B4E030 Q99542 |
Accessions | AAT97983 EAW96844 EAW96845 Q99542 AK225939 AK297999 BAG60305 AK303202 BAG64292 AL545199 BC030206 BC050368 AAH50368 BI761698 HQ448618 ADQ33096 U37791 AAC51521 U38320 AAB63007 U38321 AAB63008 U38322 AAB63009 U38431 AAC99995 X92521 CAA63299 Y08622 CAA69913 XM_006719401 XP_006719464 XM_011538358 XP_011536660 XM_011538359 XP_011536661 XR_429102 XR_944553 NM_001272101 NP_001259030 NM_002429 NP_002420 NR_073606 NM_001032360 NM_022790 NM_022792 |
Function | Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin. {ECO:0000269|PubMed:10809722, ECO:0000269|PubMed:10922468}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients. |
Human MMP19 full length protein - ab132174 from Abcam
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MMP19 peptide - ab41106 from Abcam
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MMP19 peptide - ab41107 from Abcam
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MMP19 peptide - ab41108 from Abcam
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MMP19 Antibody Blocking Peptide - LS-E2681 from LifeSpan Bioscience
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MMP19 Antibody Blocking Peptide - LS-E8128 from LifeSpan Bioscience
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MMP19 Antibody Blocking Peptide - LS-E11300 from LifeSpan Bioscience
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MMP19 Antibody Blocking Peptide - LS-E11301 from LifeSpan Bioscience
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Recombinant Human MMP-19 Protein - H00004327-P02 from Novus Biologicals
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MMP-19 Peptide - P1810 from Novus Biologicals
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MMP19-Antibody-N-term-Blocking-peptide - BP13759a from Abgent, a WuXi AppTec company
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MMP19-Antibody-C-term-Blocking-Peptide - BP6202a from Abgent, a WuXi AppTec company
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Human MMP-19 protein (Native) - orb139347 from Biorbyt
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MMP19 peptide - orb217623 from Biorbyt
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MMP19 Blocking Peptide - 33R-3981 from Fitzgerald
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MMP19 Blocking Peptide - 33R-1365 from Fitzgerald
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MMP19 Blocking Peptide - abx062954 from Abbexa
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MMP-19 - H00004327-P02 from Acris Antibodies
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MMP-19 - H00004327-P02-10 from Acris Antibodies
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MMP-19 - H00004327-P02-25 from Acris Antibodies
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MMP19 fusion protein - Ag6901 from Proteintech Group
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MMP19 fusion protein - Ag5501 from Proteintech Group
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Recombinant Human MMP19, Catalytic Domain - MMP19-161H from Creative Biomart
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Recombinant Human MMP19, None tagged - MMP19-7378H from Creative Biomart
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Recombinant Matrix Metalloproteinase 19 (MMP19) - RPB853Hu01 from Uscn Life Science Inc.
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