BPGM

Gene Symbol BPGM
Entrez Gene 669
Alt Symbol DPGM
Species Human
Gene Type protein-coding
Description 2,3-bisphosphoglycerate mutase
Other Description 2,3-bisphosphoglycerate mutase, erythrocyte|2,3-bisphosphoglycerate synthase|2,3-diphosphoglycerate mutase|BPG-dependent PGAM|bisphosphoglycerate mutase|erythrocyte 2,3-bisphosphoglycerate mutase
Swissprots A4D1N9 P07738
Accessions AAA51840 CBX85738 CBX85919 EAL24067 EAW83821 EAW83822 EAW83823 EAW83824 P07738 AB209044 BAD92281 AK097778 BAG53525 AK315439 BAG37827 BC017050 AAH17050 BM090687 BU608668 BU664387 BX473275 CB994648 CF242942 DA701935 DB047822 DB049554 HQ447339 ADQ31825 X04327 CAA27858 XM_011516527 XP_011514829 NM_001293085 NP_001280014 NM_001724 NP_001715 NM_199186 NP_954655
Function Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities.
Tissue Specificity Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto- maternal interface (at protein level). {ECO:0000269|PubMed:16246416, ECO:0000269|PubMed:3023066, ECO:0000269|PubMed:6313356}.
Top Pathways Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism

BPGM (B-11) - sc-393964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPGM (B-11): sc-393964. Western blot analysis of BPGM expression in K-562 (A) and A-431 (B) whole cell lysates and human placenta tissue extract (C).

BPGM (C-4) - sc-373819 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPGM (C-4): sc-373819. Western blot analysis of BPGM expression in human erythrocyte whole cell lysate (A) and human placenta tissue extract (B).

BPGM (L-15) - sc-82786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BPGM (L-15): sc-82786. Western blot analysis of BPGM expression in human erythrocyte whole cell lysate.

BPGM (F-2) - sc-376578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPGM (F-2): sc-376578. Western blot analysis of BPGM expression in K-562 whole cell lysate.

BPGM (Q-15) - sc-82787 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BPGM (Q-15): sc-82787. Western blot analysis of BPGM expression in human erythrocyte whole cell lysate.

Anti-BPGM antibody - ab97497 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BPGM antibody (ab97497) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-BPGM antibody - ab112957 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BPGM antibody (ab112957) at 1/100 dilution + MDA-MB-435 cell lysate at 35 µg

Anti-BPGM antibody [EPR15127] - ab186434 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15127
Anti-BPGM antibody [EPR15127] (ab186434) at 1/1000 dilution + Human placenta lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-BPGM antibody [EPR15128] - ab186739 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15128
Western blot analysis on immunoprecipitation from 1) Human blood lysate and 2) PBS, labeling BPGM using 186739 at 1/50 dilution and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG at a 1/1500 dilution.

Anti-BPGM antibody - C-terminal - ab181703 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (C-Terminus) - LS-C145075 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (C-Terminus) - LS-C153385 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259, APC) - LS-C252972 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259, AP) - LS-C252654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259, Biotin) - LS-C252973 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259, FITC) - LS-C252974 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259, Azide-free, HRP) - LS-C252976 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa229-259) - LS-C319862 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (aa110-159) - LS-C82013 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-BPGM Antibody (aa229-259, PE) - LS-C252977 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BPGM Antibody (C-Terminus) - LS-C82014 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-BPGM Antibody (aa230-259) - LS-C156845 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of BPGM (arrow) using rabbit polyclonal BPGM Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BPGM gene.

Anti-BPGM Antibody (aa1-246) IHC-plus™ - LS-B10833 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BPGM antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10833 concentration 7.5 ug/ml.

BPGM Antibody - NBP1-86064 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BPGM Antibody [NBP1-86064] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

BPGM Antibody - NBP1-86377 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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