Gene Symbol | BPGM |
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Entrez Gene | 669 |
Alt Symbol | DPGM |
Species | Human |
Gene Type | protein-coding |
Description | 2,3-bisphosphoglycerate mutase |
Other Description | 2,3-bisphosphoglycerate mutase, erythrocyte|2,3-bisphosphoglycerate synthase|2,3-diphosphoglycerate mutase|BPG-dependent PGAM|bisphosphoglycerate mutase|erythrocyte 2,3-bisphosphoglycerate mutase |
Swissprots | A4D1N9 P07738 |
Accessions | AAA51840 CBX85738 CBX85919 EAL24067 EAW83821 EAW83822 EAW83823 EAW83824 P07738 AB209044 BAD92281 AK097778 BAG53525 AK315439 BAG37827 BC017050 AAH17050 BM090687 BU608668 BU664387 BX473275 CB994648 CF242942 DA701935 DB047822 DB049554 HQ447339 ADQ31825 X04327 CAA27858 XM_011516527 XP_011514829 NM_001293085 NP_001280014 NM_001724 NP_001715 NM_199186 NP_954655 |
Function | Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities. |
Tissue Specificity | Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto- maternal interface (at protein level). {ECO:0000269|PubMed:16246416, ECO:0000269|PubMed:3023066, ECO:0000269|PubMed:6313356}. |
Top Pathways | Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism |
Human BPGM full length protein - ab95344 from Abcam
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Human BPGM full length protein - ab173072 from Abcam
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Human BPGM full length protein - ab116488 from Abcam
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BPGM Antibody Blocking Peptide - LS-E1807 from LifeSpan Bioscience
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BPGM Antibody Blocking Peptide - LS-E21301 from LifeSpan Bioscience
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BPGM Recombinant Protein - H00000669-P02 from Novus Biologicals
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BPGM Recombinant Protein - H00000669-P01 from Novus Biologicals
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Recombinant Human BPGM Protein - NBP1-44485 from Novus Biologicals
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BPGM-Antibody-C-term-Blocking-peptide - BP12615b from Abgent, a WuXi AppTec company
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BPGM Protein (OPPA02250) - OPPA02250 from Aviva Systems Biology
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Human BPGM R protein - orb163476 from Biorbyt
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Human BPGM protein - orb90045 from Biorbyt
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BPGM Blocking Peptide - 33R-2684 from Fitzgerald
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BPGM Blocking Peptide - 33R-5292 from Fitzgerald
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Bisphosphoglycerate mutase (1-259, His-tag) - AR09427PU-L from Acris Antibodies
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Bisphosphoglycerate mutase (1-259, His-tag) - AR09427PU-N from Acris Antibodies
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Bisphosphoglycerate mutase - H00000669-P01-10 from Acris Antibodies
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Bisphosphoglycerate mutase - H00000669-P01-25 from Acris Antibodies
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Bisphosphoglycerate mutase - H00000669-P02 from Acris Antibodies
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Bisphosphoglycerate mutase - H00000669-P02-10 from Acris Antibodies
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Bisphosphoglycerate mutase - H00000669-P02-25 from Acris Antibodies
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2,3-Bisphosphoglycerate Mutase, Human Recombinant - 228-12523-1 from RayBiotech
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Recombinant 2,3-Bisphosphoglycerate Mutase Human - 228-12523-2 from RayBiotech
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Recombinant 2,3-Bisphosphoglycerate Mutase Human - 228-12523-3 from RayBiotech
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BPGM, 1-259aa, Human, His-tagged, Recombinant, E.coli - 01-1812 from ARP American Research Products
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