LIN7B

Gene Symbol	LIN7B
Entrez Gene	64130
Alt Symbol	LIN-7B, MALS-2, MALS2, VELI2
Species	Human
Gene Type	protein-coding
Description	lin-7 homolog B (C. elegans)
Other Description	hLin7B|hVeli2|mammalian lin-seven protein 2|protein lin-7 homolog B|veli-2|vertebrate lin-7 homolog 2
Swissprots	Q9HAP6
Accessions	EAW52454 EAW52455 Q9HAP6 AF311862 AAG34117 AY358744 AAQ89104 BC027618 AAH27618 BM069859 XM_005259149 XP_005259206 XM_006723323 XP_006723386 XR_243950 NM_001308419 NP_001295348 NM_022165 NP_071448
Function	Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Enriched in synaptosomes and at epithelial cell-cell junctions (By similarity). Mainly basolateral in renal epithelial cells. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LIN7B full length protein - ab137156 from Abcam Category Protein Source E. coli Species Human

LIN7B Antibody Blocking Peptide - LS-E25651 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIN7B Recombinant Protein - H00064130-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

LIN7B Protein - NBP2-23198 from Novus Biologicals Category Protein Prices $309.00 Sizes 50 µg Species Human

LIN7B blocking peptide - GTX25967-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Human LIN7B protein - orb191089 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

LIN7B protein (His tag) - 80R-2603 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

LIN7B Peptide - AC21-0482-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

LIN7B (1-207, His-tag) - AR50649PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

LIN7B (1-207, His-tag) - AR50649PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

LIN7B - H00064130-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

LIN7B - H00064130-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

LIN7B, 1-207aa, Human, His tag, E.coli - 01-P1825 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

LIN7B Peptide - 45-832P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Mouse, Rat

LIN7B fusion protein - Ag3437 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human lin-7 homolog B (C. elegans), His-tagged - LIN7B-386H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein lin-7 homolog B(LIN7B) - CSB-YP872531HU CSB-EP872531HU CSB-BP872531HU CSB-MP872531HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LIN7B, 1-207aa, Human, His tag, E.coli - ATGP1825 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

LIN7B Protein (Recombinant) - abx262566 from Abbexa Category Protein

LIN7B - TP305598 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

LIN7B/MALS-2, Peptide - MBS425961 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

LIN7B Protein - NBP1-92072PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

LIN7B-Blocking-Peptide-N-term - BP19782a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LIN7B Peptide, Human - M34GP08729H from Creative Peptides Category Peptide Source Synthetic. Species Human

LIN7B Antibody - SH-A13325 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

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