POC1B

Gene Symbol POC1B
Entrez Gene 282809
Alt Symbol CORD20, PIX1, TUWD12, WDR51B
Species Human
Gene Type protein-coding
Description POC1 centriolar protein B
Other Description POC1 centriolar protein homolog B|WD repeat-containing protein 51B|proteome of centriole protein 1B
Swissprots G3V1X0 Q8TC44
Accessions BAB69430 CAF86799 CAF86800 EAW97425 EAW97426 EAW97427 Q8TC44 AB053266 BAB69057 AK027829 AK074772 BAC11198 AK123106 AK123625 BAC85666 AK295596 BAG58486 AL832918 CAH10775 AW149266 BC026080 AAH26080 BU521431 BX648293 DA851891 DC354425 EF011619 ABK41109 HQ447314 ADQ31801 NM_001199777 NP_001186706 NM_172240 NP_758440 NR_037659 NR_037660
Function Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745). {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:20008567, ECO:0000269|PubMed:23015594, ECO:0000269|PubMed:25044745}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:23015594}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:20008567}. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles. Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer. {ECO:0000250|UniProtKB:Q8BHD1}.
Tissue Specificity Expressed in the retina. {ECO:0000269|PubMed:25044745}.

Human WDR51B full length protein - ab166110 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166110 on a 12.5% SDS-PAGE stained with Coomassie Blue.

POC1B / WDR51B Antibody Blocking Peptide - LS-E671 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

POC1B / WDR51B Antibody Blocking Peptide - LS-E20106 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human WDR51B Protein - H00282809-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

WDR51B-Antibody-C-term-Blocking-peptide - BP11016b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

WDR51B Blocking Peptide - 33R-3452 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

WDR51B - H00282809-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

WDR51B - H00282809-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

WDR51B fusion protein - ag20160 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

WDR51B fusion protein - ag20200 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human POC1 centriolar protein homolog B(POC1B) - CSB-YP855046HU CSB-EP855046HU CSB-BP855046HU CSB-MP855046HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

POC1B Protein - abx163430 from Abbexa

Category Protein
Species Human, Mouse, Rat

WDR51B - TP305470 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
WDR51B

POC1 centriolar protein homolog B (POC1B), Recombinant Protein - MBS1341006 from MyBioSource

Category Protein
Prices $1,260.00, $1,260.00, $1,480.00, $1,480.00, $2,060.00, $2,060.00, $2,525.00, $2,525.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

WDR51B Protein - NBP1-92584PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

WDR51B-Blocking-Peptide-C-term - BP21756b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

POC1B Peptide, Human - M34GP12049H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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