POC1B

Gene Symbol POC1B
Entrez Gene 282809
Alt Symbol CORD20, PIX1, TUWD12, WDR51B
Species Human
Gene Type protein-coding
Description POC1 centriolar protein B
Other Description POC1 centriolar protein homolog B|WD repeat-containing protein 51B|proteome of centriole protein 1B
Swissprots G3V1X0 Q8TC44
Accessions BAB69430 CAF86799 CAF86800 EAW97425 EAW97426 EAW97427 Q8TC44 AB053266 BAB69057 AK027829 AK074772 BAC11198 AK123106 AK123625 BAC85666 AK295596 BAG58486 AL832918 CAH10775 AW149266 BC026080 AAH26080 BU521431 BX648293 DA851891 DC354425 EF011619 ABK41109 HQ447314 ADQ31801 NM_001199777 NP_001186706 NM_172240 NP_758440 NR_037659 NR_037660
Function Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745). {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:20008567, ECO:0000269|PubMed:23015594, ECO:0000269|PubMed:25044745}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:23015594}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:20008567}. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles. Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer. {ECO:0000250|UniProtKB:Q8BHD1}.
Tissue Specificity Expressed in the retina. {ECO:0000269|PubMed:25044745}.

WDR51B (D-20) - sc-244633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-WDR51B antibody - ab170121 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-WDR51B antibody (ab170121) at 1/500 dilution + Raji cell lysate

Anti-WDR51B antibody - ab84919 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-WDR51B antibody (ab84919) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal lung lysate at 10 µgSecondaryanti-Rabbit IgG HRP at 1/50000 dilution

Anti-WDR51B antibody - ab169264 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-WDR51B antibody (ab169264) at 1/500 dilutionLane 1 : WDR51B transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-POC1B / WDR51B Antibody (aa321-350, AP) - LS-C242711 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350, APC) - LS-C242712 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350, FITC) - LS-C242715 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350, Azide-free, HRP) - LS-C247247 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350, PE) - LS-C242719 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350, Biotin) - LS-C242714 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa321-350) - LS-C326340 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POC1B / WDR51B Antibody (aa72-121) - LS-C102675 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POC1B / WDR51B antibody LS-C102675 Western blot of Fetal Lung lysate.

Anti-POC1B / WDR51B Antibody (aa321-350) - LS-C160592 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
WDR51B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

WDR51B Antibody - NBP1-92584 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WDR51B Antibody [NBP1-92584] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY406759)

WDR51B Antibody - NBP1-56307 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

WDR51B Antibody - H00282809-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: WDR51B Antibody [H00282809-B01] - analysis of WDR51B expression in transfected 293T cell line by WDR51B MaxPab polyclonal antibody. Lane 1: WDR51B transfected lysate (52.58 KDa). Lane 2: Non-transfected lysate.

Anti-POC1B antibody produced in rabbit - HPA038841 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-POC1B: <B>Cat. No. HPA038841</B>: Immunohistochemical staining of human duodenum shows moderate granular cytoplasmic positivity in glandular cells.

ANTI-WDR51B(C-TERMINAL) antibody produced in rabbit - SAB1305379 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal

Anti-POC1B (47-60) antibody produced in rabbit - SAB1103262 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human POC1B was separated on SDS-PAGE, blotted with Anti-POC1B (47-60) (<B>Cat. No. SAB1103262</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-WDR51B antibody produced in rabbit - SAB2102705 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-WDR51B: <B>Cat. No.SAB2102705</B>: WDR51B in Fetal Lung tissue lysate with WDR51B antibody at 1.0 μg/mL.

Anti-POC1B (6-20) antibody produced in rabbit - SAB1103261 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human POC1B was separated on SDS-PAGE, blotted with Anti-POC1B (6-20) (<B>Cat. No. SAB1103261</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + POC1B immunizing peptide (human, 6-20)

WDR51B antibody - N-terminal region (ARP55620_P050) - ARP55620_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

POC1B Antibody - C-terminal region (OAAB01036) - OAAB01036 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

WDR51B-Antibody-C-term - AP11016b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of WDR51B Antibody (C-term) Pab (Cat. #AP11016b) pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. WDR51B Antibody (C-term) (arrow) was detected using the purified Pab.

WDR51B antibody - 70R-3215 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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