POC1B

Gene Symbol POC1B
Entrez Gene 282809
Alt Symbol CORD20, PIX1, TUWD12, WDR51B
Species Human
Gene Type protein-coding
Description POC1 centriolar protein B
Other Description POC1 centriolar protein homolog B|WD repeat-containing protein 51B|proteome of centriole protein 1B
Swissprots G3V1X0 Q8TC44
Accessions BAB69430 CAF86799 CAF86800 EAW97425 EAW97426 EAW97427 Q8TC44 AB053266 BAB69057 AK027829 AK074772 BAC11198 AK123106 AK123625 BAC85666 AK295596 BAG58486 AL832918 CAH10775 AW149266 BC026080 AAH26080 BU521431 BX648293 DA851891 DC354425 EF011619 ABK41109 HQ447314 ADQ31801 NM_001199777 NP_001186706 NM_172240 NP_758440 NR_037659 NR_037660
Function Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745). {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:20008567, ECO:0000269|PubMed:23015594, ECO:0000269|PubMed:25044745}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:23015594}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:20008567}. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles. Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer. {ECO:0000250|UniProtKB:Q8BHD1}.
Tissue Specificity Expressed in the retina. {ECO:0000269|PubMed:25044745}.

WDR51B CRISPR/Cas9 KO Plasmid (h) - sc-415281 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B HDR Plasmid (h) - sc-415281-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B Double Nickase Plasmid (h) - sc-415281-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B Double Nickase Plasmid (h2) - sc-415281-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B CRISPR Activation Plasmid (h) - sc-415281-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B CRISPR Activation Plasmid (h2) - sc-415281-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B Lentiviral Activation Particles (h) - sc-415281-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B Lentiviral Activation Particles (h2) - sc-415281-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR51B siRNA (h) - sc-96038 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WDR51B shRNA Plasmid (h) - sc-96038-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WDR51B shRNA (h) Lentiviral Particles - sc-96038-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU028001 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17075 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17075 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

POC1B siRNA (Human) - CRJ6853 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human POC1B (NM_172240.2) - SHH378920 from Creative biogene

Category siRNA
Species Reactivities Human

POC1B shRNA Plasmid (Human) - CHJ6853 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POC1B miRNA 3'UTR clone - MiUTR3H-13404 from Creative biogene

Species Reactivities Human
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