MYCN

Gene Symbol MYCN
Entrez Gene 4613
Alt Symbol MODED, N-myc, NMYC, ODED, bHLHe37
Species Human
Gene Type protein-coding
Description v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
Other Description N-myc proto-oncogene protein|class E basic helix-loop-helix protein 37|neuroblastoma MYC oncogene|neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene|oncogene NMYC|pp65/67
Swissprots Q6LDT9 P04198 Q53XS5
Accessions AAA36370 AAA36371 AAA59885 AAK38075 AAY14952 CAA27037 CAA27038 CAA68677 CAA68678 CAB37871 CAB44703 CBI12210 CCW44112 EAX00885 EAX00886 EAX00887 EAX00888 P04198 AF320053 AAG40001 AI962624 AK298225 BAG60495 AK299495 BAG61453 BC002712 AAH02712 BT007384 AAP36048 BU167361 M55330 NM_001293228 NP_001280157 NM_001293231 NP_001280160 NM_001293233 NP_001280162 NM_005378 NP_005369
Function May function as a transcription factor.
Subcellular Location Nucleus.
Top Pathways Transcriptional misregulation in cancer

N-Myc Antibody - 9405 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from the IMR-32 neuroblastoma cell line, using N-Myc Antibody.

N-Myc (2) - sc-142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
N-Myc (2): sc-142. Western blot analysis of N-Myc expression in CCRF-HSB-2 (A), H4 (B), HuT 78 (C), BJAB (D) and Ramos (E) whole cell lysates.

N-Myc (B8.4.B) - sc-53993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
N-Myc (B8.4.B): sc-53993. Western blot analysis of N-Myc expression in IMR-32 (A) and SH-SY5Y (B) whole cell lysates.

N-Myc (C-19) - sc-791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
N-Myc (C-19): sc-791. Western blot analysis of N-Myc expression in non-transfected: sc-117752 (A) and mouse N-Myc transfected: sc-121906 (B) 293T whole cell lysates.

N-Myc (H-50) - sc-22835 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

N-Myc (NCM II 100) - sc-56729 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
N-Myc (NCM II 100): sc-56729. Western blot analysis of N-Myc expression in IMR-32 (A), SH-SY5Y (B) and BE (2)-M17 (C) whole cell lysates.

N-Myc (NMYC-1) - sc-80546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
N-Myc (NMYC-1): sc-80546. Western blot analysis of N-Myc expression in non-transfected: sc-117752 (A) and mouse N-Myc transfected: sc-121906 (B) 293T whole cell lysates.

N-Myc (3C165) - sc-71633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
N-Myc (3C165): sc-71633. Western blot analysis of N-Myc expression in non-transfected: sc-117752 (A) and mouse N-Myc transfected: sc-121906 (B) 293T whole cell lysates.

Anti-n-Myc antibody - ab24193 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-n-Myc antibody (ab24193) at 1 µg/mlLane 1 : Heart (Human) Whole Cell Lysate - fetal normal tissueLane 2 : Heart (Mouse) Tissue LysateLane 3 : Skeletal Muscle (Mouse) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG VHH Single Domain Antibody (HRP) (ab191866) at 1/50000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-n-Myc antibody - ab198912 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling n-Myc with ab198912 at a 1/50 dilution.

Anti-n-Myc antibody [6A4I] - ab119701 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6A4I
Overlay histogram showing SH-SH5Y cells stained with ab119701 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab119701, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was a goat anti-mouse Alexa Fluor® 488 (IgG; H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in SH-SY5Y cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-n-Myc antibody [NCM II 100] - ChIP Grade - ab16898 from Abcam

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone NCM II 100
Immunoprecipitation of N-Myc from S35 methionine-labeled IMR-5 cells using ab16898 (lane 1) and Normal Mouse IgG (lane 2). ab16898 used at 1 mg/sample.

Anti-n-Myc antibody - C-terminal - ab135652 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-n-Myc antibody - C-terminal (ab135652) at 1/50 dilution + CEM cell line lysate at 35 µg

Anti-MYCN / N-myc Antibody (clone 1A8) - LS-C25775 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A8

Anti-MYCN / N-myc Antibody (aa327-339, clone NMYC-1) - LS-C49182 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone NMYC-1

Anti-MYCN / N-myc Antibody - LS-C72951 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-MYCN / N-myc Antibody (aa337-349) - LS-C91107 from LifeSpan Bioscience

Prices $495.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-MYCN / N-myc Antibody (clone 986C1a) - LS-C184359 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 986C1a

Anti-MYCN / N-myc Antibody (phospho-Ser54) - LS-C287127 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MYCN / N-myc Antibody (clone GF1) - LS-C189903 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-MYCN / N-myc Antibody (C-Terminus) - LS-C210148 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-MYCN / N-myc Antibody (aa342-391) - LS-C31104 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Fetal Heart Lysate

Anti-MYCN / N-myc Antibody - LS-C136849 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MYCN / N-myc Antibody (clone 4H4) - LS-C139070 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H4
Detection limit for recombinant GST tagged MYCN is approximately 1 ng/ml as a capture antibody.

Anti-MYCN / N-myc Antibody - LS-C335093 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain, using MYCN antibody.
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