| Gene Symbol |
GPX3
|
| Entrez Gene |
2878
|
| Alt Symbol |
GPx-P, GSHPx-3, GSHPx-P
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutathione peroxidase 3
|
| Other Description |
GPx-3|extracellular glutathione peroxidase|glutathione peroxidase 3 (plasma)|plasma glutathione peroxidase
|
| Swissprots |
Q86W78 Q9NZ74 Q9UEL1 O43787 P22352
|
| Accessions |
AAP50261 BAA03862 BAA03863 BAA03864 EAW61692 EAW61693 P22352 AF217787 AAF43005 AK310242 AL036834 BC013218 BC013601 AAH13601 BC025956 BC035841 AAH35841 BC050378 AAH50378 BC066949 AAH66949 BI522602 D00632 BAA00525 X58295 CAA41228 NM_002084 NP_002075
|
| Function |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Secreted in plasma.
|
| Top Pathways |
Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism
|