Gene Symbol | GPX3 |
---|---|
Entrez Gene | 2878 |
Alt Symbol | GPx-P, GSHPx-3, GSHPx-P |
Species | Human |
Gene Type | protein-coding |
Description | glutathione peroxidase 3 |
Other Description | GPx-3|extracellular glutathione peroxidase|glutathione peroxidase 3 (plasma)|plasma glutathione peroxidase |
Swissprots | Q86W78 Q9NZ74 Q9UEL1 O43787 P22352 |
Accessions | AAP50261 BAA03862 BAA03863 BAA03864 EAW61692 EAW61693 P22352 AF217787 AAF43005 AK310242 AL036834 BC013218 BC013601 AAH13601 BC025956 BC035841 AAH35841 BC050378 AAH50378 BC066949 AAH66949 BI522602 D00632 BAA00525 X58295 CAA41228 NM_002084 NP_002075 |
Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
Subcellular Location | Secreted. |
Tissue Specificity | Secreted in plasma. |
Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |