Gene Symbol | GPX3 |
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Entrez Gene | 2878 |
Alt Symbol | GPx-P, GSHPx-3, GSHPx-P |
Species | Human |
Gene Type | protein-coding |
Description | glutathione peroxidase 3 |
Other Description | GPx-3|extracellular glutathione peroxidase|glutathione peroxidase 3 (plasma)|plasma glutathione peroxidase |
Swissprots | Q86W78 Q9NZ74 Q9UEL1 O43787 P22352 |
Accessions | AAP50261 BAA03862 BAA03863 BAA03864 EAW61692 EAW61693 P22352 AF217787 AAF43005 AK310242 AL036834 BC013218 BC013601 AAH13601 BC025956 BC035841 AAH35841 BC050378 AAH50378 BC066949 AAH66949 BI522602 D00632 BAA00525 X58295 CAA41228 NM_002084 NP_002075 |
Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
Subcellular Location | Secreted. |
Tissue Specificity | Secreted in plasma. |
Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |
GPx-3 CRISPR/Cas9 KO Plasmid (h) - sc-402413 from Santa Cruz Biotechnology
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GPx-3 HDR Plasmid (h) - sc-402413-HDR from Santa Cruz Biotechnology
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GPx-3 Double Nickase Plasmid (h) - sc-402413-NIC from Santa Cruz Biotechnology
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GPx-3 Double Nickase Plasmid (h2) - sc-402413-NIC-2 from Santa Cruz Biotechnology
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GPx-3 CRISPR Activation Plasmid (h) - sc-402413-ACT from Santa Cruz Biotechnology
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GPx-3 CRISPR Activation Plasmid (h2) - sc-402413-ACT-2 from Santa Cruz Biotechnology
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GPx-3 Lentiviral Activation Particles (h) - sc-402413-LAC from Santa Cruz Biotechnology
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GPx-3 Lentiviral Activation Particles (h2) - sc-402413-LAC-2 from Santa Cruz Biotechnology
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GPx-3 siRNA (h) - sc-62417 from Santa Cruz Biotechnology
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GPx-3 shRNA Plasmid (h) - sc-62417-SH from Santa Cruz Biotechnology
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GPx-3 shRNA (h) Lentiviral Particles - sc-62417-V from Santa Cruz Biotechnology
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Glutathione Peroxidase 3/GPX3 RNAi - H00002878-R01 from Novus Biologicals
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MISSION® esiRNA - EHU224171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9647 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9647 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06540 from Sigma-Aldrich
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GPX3 siRNA (Human) - CRH1935 from Cohesion Biosciences
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GPX3 - MBS8234165 from MyBioSource
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shRNA set against Human GPX3 (NM_002084.3) - SHH307386 from Creative biogene
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shRNA set against Human GPX3(NM_002084.3) - SHH102467 from Creative biogene
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Human GPX3 siRNA - orb262437 from Biorbyt
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GPX3 shRNA Plasmid (Human) - CHH1935 from Cohesion Biosciences
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GPX3 miRNA 3'UTR clone - MiUTR1H-04246 from Creative biogene
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