Gene Symbol | KRTAP12-1 |
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Entrez Gene | 353332 |
Alt Symbol | KAP12.1, KRTAP12.1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 12-1 |
Other Description | high sulfur keratin-associated protein 12.1|keratin-associated protein 12-1|keratin-associated protein 12.1 |
Swissprots | P59990 Q0VAS3 |
Accessions | EAX09405 P59990 AB076363 BAD01550 AJ566388 CAD97468 BC119713 AAI19714 BC120942 AAI20943 BC127648 AAI27649 NM_181686 NP_859014 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
Recombinant Human KRTAP12-1 - KRTAP12-1-1550H from Creative Biomart
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Recombinant Human Keratin-associated protein 12-1(KRTAP12-1) - CSB-YP012605HU CSB-EP012605HU CSB-BP012605HU CSB-MP012605HU from Cusabio
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KRTAP12-1 Peptide, Human - M34GP08424H from Creative Peptides
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Keratin-associated protein 12-1 (KRTAP12-1), Recombinant Protein - MBS950598 from MyBioSource
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