CDCA7L

Gene Symbol CDCA7L
Entrez Gene 55536
Alt Symbol JPO2, R1, RAM2
Species Human
Gene Type protein-coding
Description cell division cycle associated 7-like
Other Description cell division cycle-associated 7-like protein|transcription factor RAM2
Swissprots Q6PIL4 Q8IXN5 B4DUT3 Q9NPV2 A6NF50 Q96C70 A4D141 B3KTR5 Q86YT0 Q9H9A2 Q96GN5 C9K0Y1
Accessions AAS02007 EAL24271 EAW93740 EAW93741 EAW93742 EAW93743 EAW93744 Q96GN5 AA922229 AK022955 BAB14330 AK095965 BAG53177 AK292490 BAF85179 AK300781 BAG62445 AL359619 CAB94887 AL576822 AY161168 AAO17570 AY161169 AAO17571 BC009352 AAH09352 BC014630 AAH14630 BC025242 AAH25242 BC032576 AAH32576 BC039823 AAH39823 BI493265 BU753973 BX112809 BX422040 DA041070 DC331792 HQ448527 ADQ33006 NM_001127370 NP_001120842 NM_001127371 NP_001120843 NM_018719 NP_061189
Function Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933, ECO:0000269|PubMed:16829576}.
Subcellular Location Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Tissue Specificity Ubiquitous. Overexpressed in medulloblastoma. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933}.

CdcA7L (C-13) - sc-160224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CdcA7L (C-13): sc-160224. Western blot analysis of CdcA7L expression in Hep G2 whole cell lysate.

CdcA7L (E-15) - sc-160225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CdcA7L (E-15): sc-160225. Western blot analysis of CdcA7L expression in HeLa (A), K-562 (B), 293T (C), HCT-116 (D) and U-87 MG (E) whole cell lysates and human tonsil tissue extract (F).

Anti-CDCA7L antibody - ab70637 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDCA7L antibody (ab70637) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-CDCA7L antibody [1A12] - ab180480 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A12
All lanes : Anti-CDCA7L antibody [1A12] (ab180480) at 2000 Lane 1 : Lysate from HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : Lysate from HEK293T cells transfected with pCMV6-ENTRY CDCA7L cDNALysates/proteins at 5 µg per lane.

Anti-CDCA7L Antibody (aa1-337, clone 2C1) - LS-C336769 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C1
IHC of paraffin-embedded Human bladder tissue using anti-CDCA7L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-CDCA7L Antibody (aa1-337, clone 6C6) - LS-C336756 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C6
IHC of paraffin-embedded Human tonsil using anti-CDCA7L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-CDCA7L Antibody (aa1-337, clone 1A12) - LS-C336741 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A12
IHC of paraffin-embedded Human tonsil using anti-CDCA7L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-CDCA7L Antibody (aa1-337, clone 3B5) - LS-C336771 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B5
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDCA7L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-CDCA7L Antibody (C-Terminus) - LS-C71154 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-CDCA7L Antibody (C-Terminus) - LS-C287693 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CDCA7L Antibody - LS-C155635 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE CDCA7L antibody diluted at 1:1000

Anti-CDCA7L Antibody (aa170-220) - LS-C148695 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of CDCA7L/RAM2 in HCT-116 cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) NIH 3T3 cell lysate using LS-C148695 at 4 ug/ml and 2 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Anti-CDCA7L Antibody (C-Terminus) - LS-C112020 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CDCA7L antibody LS-C112020 Western blot of COLO205 cell lysate.

Anti-CDCA7L Antibody (aa290-317) - LS-C204049 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CDCA7L Antibody western blot of 293,A2058,Ramos,U251,U937 cell line lysates (35 ug/lane). The CDCA7L antibody detected the CDCA7L protein (arrow).

Anti-CDCA7L Antibody (aa1-337, clone 4A2) - LS-C338633 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4A2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDCA7L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDCA7L.

CDCA7L Antibody - NBP2-24472 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CDCA7L Antibody [NBP2-24472] - Analysis of CDCA7L/RAM2 in HCT-116 cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) NIH 3T3 cell lysate using NBP2-24472 at 4 ug/ml and 2 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

CDCA7L Antibody - NBP1-83074 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CDCA7L Antibody [NBP1-83074] - Staining of human cell line U-2 OS shows positivity in nucleus, nucleoli & cytoplasm.

CDCA7L Antibody - NB110-40559 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CDCA7L Antibody [NB110-40559] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit antiJPO2/RAM2 antibody BL3661 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate (B). Detection: Chemiluminescence with exposure times of 30 seconds (A and B).

CDCA7L Antibody - NBP2-15839 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CDCA7L Antibody [NBP2-15839] - Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE gel, diluted at 1:1000.

CDCA7L Polyclonal Antibody - bs-5963R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CDCA7L antibody produced in rabbit - HPA027169 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CDCA7L: <B>Cat. No. HPA027169</B>: Immunohistochemical staining of human appendix shows strong nuclear positivity in lymphoid reaction center cells.

Anti-CDCA7L antibody produced in rabbit - SAB2701492 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CDCA7L: <B>Cat. No. SAB2701492</B>: Western Blot analysis of CDCA7L in extracts from <B>Lanes</B><BR/>A. U87-MG using <B>Cat. No. SAB2701492</B> at a 1:1000 dilution.

Anti-CDCA7L (261-275) antibody produced in rabbit - SAB1102060 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human CDCA7L was separated on SDS-PAGE, blotted with Anti-CDCA7L (261-275) (<B>Cat. No. SAB1102060</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

CDCA7L antibody - middle region (ARP57292_P050) - ARP57292_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDCA7L-Antibody-C-term - AP20468b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
CDCA7L Antibody (C-term) (Cat. #AP20468b) western blot analysis in 293,A2058,Ramos,U251,U937 cell line lysates (35ug/lane).This demonstrates the CDCA7L antibody detected the CDCA7L protein (arrow).
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