CDCA7L

Gene Symbol CDCA7L
Entrez Gene 55536
Alt Symbol JPO2, R1, RAM2
Species Human
Gene Type protein-coding
Description cell division cycle associated 7-like
Other Description cell division cycle-associated 7-like protein|transcription factor RAM2
Swissprots Q6PIL4 Q8IXN5 B4DUT3 Q9NPV2 A6NF50 Q96C70 A4D141 B3KTR5 Q86YT0 Q9H9A2 Q96GN5 C9K0Y1
Accessions AAS02007 EAL24271 EAW93740 EAW93741 EAW93742 EAW93743 EAW93744 Q96GN5 AA922229 AK022955 BAB14330 AK095965 BAG53177 AK292490 BAF85179 AK300781 BAG62445 AL359619 CAB94887 AL576822 AY161168 AAO17570 AY161169 AAO17571 BC009352 AAH09352 BC014630 AAH14630 BC025242 AAH25242 BC032576 AAH32576 BC039823 AAH39823 BI493265 BU753973 BX112809 BX422040 DA041070 DC331792 HQ448527 ADQ33006 NM_001127370 NP_001120842 NM_001127371 NP_001120843 NM_018719 NP_061189
Function Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933, ECO:0000269|PubMed:16829576}.
Subcellular Location Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Tissue Specificity Ubiquitous. Overexpressed in medulloblastoma. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933}.

Human CDCA7L full length protein - ab163119 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab163119 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CDCA7L Antibody Blocking Peptide - LS-E20909 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

R1 / RRM1 Antibody Blocking Peptide - LS-E16768 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CDCA7L Protein - H00055536-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CDCA7L Blocking Peptide - 33R-7245 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CDCA7L / JPO2 - H00055536-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CDCA7L / JPO2 - H00055536-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CDCA7L fusion protein - ag10944 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

CDCA7L fusion protein - ag10706 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Ribonucleotide Reductase M1 (RRM1) - RPF914Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Cell division cycle-associated 7-like protein(CDCA7L) - CSB-YP850301HU CSB-EP850301HU CSB-BP850301HU CSB-MP850301HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Cell division cycle-associated 7-like protein (CDCA7L), Recombinant Protein - MBS1308438 from MyBioSource

Category Protein
Prices $1,235.00, $1,235.00, $1,455.00, $1,455.00, $2,005.00, $2,005.00, $2,470.00, $2,470.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CDCA7L Recombinant Protein Antigen - NBP1-83074PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CDCA7L Antibody - SH-A10959 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Species Human, Mouse, Rat

CDCA7L-Blocking-Peptide-C-term - BP20468b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CDCA7L Peptide, Human - M34GP02825H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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