Gene Symbol | TARBP1 |
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Entrez Gene | 6894 |
Alt Symbol | TRM3, TRP-185, TRP185 |
Species | Human |
Gene Type | protein-coding |
Description | TAR (HIV-1) RNA binding protein 1 |
Other Description | TAR (HIV) RNA binding protein 1|TAR (HIV) RNA-binding protein 1|TAR RNA loop binding protein|TAR RNA-binding protein 1|TAR RNA-binding protein of 185 kDa|probable methyltransferase TARBP1|tRNA methyltransferase 3 homolog |
Swissprots | Q9H581 Q13395 |
Accessions | EAW69993 Q13395 AA714641 AK055044 BC016023 BC156249 AAI56250 U38847 AAC50379 XM_005273234 XP_005273291 XM_006711812 XP_006711875 XM_011544263 XP_011542565 XM_011544264 XP_011542566 XM_011544265 XP_011542567 XR_949155 XR_949156 XR_949157 XR_949158 NM_005646 NP_005637 |
Function | Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA. {ECO:0000269|PubMed:7638159, ECO:0000269|PubMed:8626763, ECO:0000269|PubMed:8846792}. |
TARBP1 (C-14) - sc-104688 from Santa Cruz Biotechnology
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TARBP1 (H-220) - sc-368290 from Santa Cruz Biotechnology
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TARBP1 (N-12) - sc-104690 from Santa Cruz Biotechnology
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Anti-TARBP1 antibody - ab129519 from Abcam
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Anti-TARBP1 antibody - ab115896 from Abcam
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Anti-TARBP1 antibody - ab42871 from Abcam
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Anti-TARBP1 antibody [ EPR8727] - ab150412 from Abcam
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Anti-TRM3 / TARBP1 Antibody (aa1571-1621) - LS-C290291 from LifeSpan Bioscience
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Anti-TRM3 / TARBP1 Antibody - LS-C335633 from LifeSpan Bioscience
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Anti-TRM3 / TARBP1 Antibody (Internal) IHC-plus⢠- LS-B596 from LifeSpan Bioscience
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TARBP1 Antibody - NBP1-03040 from Novus Biologicals
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TARBP1 Antibody - NBP1-76400 from Novus Biologicals
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TARBP1 Antibody - 30720002 from Novus Biologicals
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Anti-TARBP1 antibody produced in rabbit - HPA024632 from Sigma-Aldrich
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Anti-TRBP1 antibody produced in rabbit - SAB3500370 from Sigma-Aldrich
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TARBP1 Polyclonal Antibody - A6073 from ABclonal
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TARBP1 Antibody - abx004676 from Abbexa
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TARBP1 antibody - AP07783PU-N from Acris Antibodies
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TARBP1 (Center) antibody - AP30940PU-N from Acris Antibodies
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TARBP1 antibody - H00006894-B01P from Acris Antibodies
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TARBP1 antibody - PAB12981 from Acris Antibodies
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Rabbit Anti-Human TRM3 / TARBP1 (Internal) - 119-11732 from RayBiotech
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Anti-TARBP1, Polyclonal Antibody - 25-A6073 from ARP American Research Products
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TRBP1 Antibody - 4011 from ProSci
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TARBP1 antibody - STJ27867 from St John's Laboratory Ltd
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