Gene Symbol | TARBP1 |
---|---|
Entrez Gene | 6894 |
Alt Symbol | TRM3, TRP-185, TRP185 |
Species | Human |
Gene Type | protein-coding |
Description | TAR (HIV-1) RNA binding protein 1 |
Other Description | TAR (HIV) RNA binding protein 1|TAR (HIV) RNA-binding protein 1|TAR RNA loop binding protein|TAR RNA-binding protein 1|TAR RNA-binding protein of 185 kDa|probable methyltransferase TARBP1|tRNA methyltransferase 3 homolog |
Swissprots | Q9H581 Q13395 |
Accessions | EAW69993 Q13395 AA714641 AK055044 BC016023 BC156249 AAI56250 U38847 AAC50379 XM_005273234 XP_005273291 XM_006711812 XP_006711875 XM_011544263 XP_011542565 XM_011544264 XP_011542566 XM_011544265 XP_011542567 XR_949155 XR_949156 XR_949157 XR_949158 NM_005646 NP_005637 |
Function | Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA. {ECO:0000269|PubMed:7638159, ECO:0000269|PubMed:8626763, ECO:0000269|PubMed:8846792}. |
TARBP1 CRISPR/Cas9 KO Plasmid (h) - sc-411029 from Santa Cruz Biotechnology
|
||||||||
TARBP1 HDR Plasmid (h) - sc-411029-HDR from Santa Cruz Biotechnology
|
||||||||
TARBP1 Double Nickase Plasmid (h) - sc-411029-NIC from Santa Cruz Biotechnology
|
||||||||
TARBP1 Double Nickase Plasmid (h2) - sc-411029-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TARBP1 CRISPR Activation Plasmid (h) - sc-411029-ACT from Santa Cruz Biotechnology
|
||||||||
TARBP1 CRISPR Activation Plasmid (h2) - sc-411029-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TARBP1 Lentiviral Activation Particles (h) - sc-411029-LAC from Santa Cruz Biotechnology
|
||||||||
TARBP1 Lentiviral Activation Particles (h2) - sc-411029-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TARBP1 siRNA (h) - sc-88496 from Santa Cruz Biotechnology
|
||||||||
TARBP1 shRNA Plasmid (h) - sc-88496-SH from Santa Cruz Biotechnology
|
||||||||
TARBP1 shRNA (h) Lentiviral Particles - sc-88496-V from Santa Cruz Biotechnology
|
||||||||
TARBP1 RNAi - H00006894-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU027861 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21002 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21002 from Sigma-Aldrich
|
||||||||
TARBP1 siRNA (Human) - CRH4721 from Cohesion Biosciences
|
||||||||
TARBP1 - MBS8203633 from MyBioSource
|
||||||||
shRNA set against Human TARBP1 (NM_005646.3) - SHH423072 from Creative biogene
|
||||||||
shRNA set against Mouse Tardbp(NM_145556.4) - SHL056268 from Creative biogene
|
||||||||
Human TARBP1 siRNA - orb265223 from Biorbyt
|
||||||||
TARBP1 shRNA Plasmid (Human) - CHH4721 from Cohesion Biosciences
|
||||||||
TARBP1 miRNA 3'UTR clone - MiUTR1H-10180 from Creative biogene
|