Gene Symbol | Bcl2l11 |
---|---|
Entrez Gene | 12125 |
Alt Symbol | 1500006F24Rik, Bim, Bod, bcl2-L-11 |
Species | Mouse |
Gene Type | protein-coding |
Description | BCL2-like 11 (apoptosis facilitator) |
Other Description | Bcl2 interacting mediator of cell death|bcl-2-like protein 11|bcl2-interacting mediator of cell death |
Swissprots | O54920 O54919 O54918 A2ALQ6 |
Accessions | EDL28212 EDL28213 EDL28214 O54918 AA275665 AA881651 AF032459 AAC40029 AF032460 AAC40030 AF032461 AAC40031 AK011490 AK031285 AK037885 AK050192 AK082613 BAC38548 AK150464 BAE29581 AK152472 BAE31246 AK153542 BAE32079 AK162975 BAE37144 AK177547 BC019556 AAH19556 BC058175 AAH58175 BE136124 CA321725 CB521709 XM_006498614 XP_006498677 XM_006498615 XP_006498678 XM_006498616 XP_006498679 XM_006498617 XP_006498680 NM_001284410 NP_001271339 NM_001291016 NP_001277945 NM_009754 NP_033884 NM_207680 NP_997563 NM_207681 NP_997564 |
Function | Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent. {ECO:0000269|PubMed:9430630}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:9430630}; Peripheral membrane protein {ECO:0000269|PubMed:9430630}. Mitochondrion {ECO:0000250}. Note=Associated with intracytoplasmic membranes. |
Tissue Specificity | Expressed in a number of B- and T-lymphoid cell lines. {ECO:0000269|PubMed:9430630}. |
Top Pathways | PI3K-Akt signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD) |
Phospho-Bim (Ser55) Antibody - 4550 from Cell Signaling Technology
|
||||||||||
Bim (Ham 151-149) - sc-130511 from Santa Cruz Biotechnology
|
||||||||||
Bim EL/L (M-20) - sc-27985 from Santa Cruz Biotechnology
|
||||||||||
Anti-Bim antibody [Ham151-149] - ab93166 from Abcam
|
||||||||||
Bim Antibody (151-149) - NBP1-40988 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Biotin] - NBP1-40837 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 350] - NBP1-40988UV from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Alexa Fluor (R) 700] - NBP1-40988AF700 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Alexa Fluor (R) 647] - NBP1-40988AF647 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Alexa Fluor (R) 488] - NBP1-40988AF488 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Alexa Fluor (R) 405] - NBP1-40988AF405 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [7C] - NBP1-40988V2 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 755] - NBP1-40988IR from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 405] - NBP1-40988V from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [PE] - NBP1-40988PE from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [PerCP] - NBP1-40988PCP from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [Allophycocyanin] - NBP1-40988APC from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 488] - NBP1-40988G from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 405LS] - NBP1-40988V3 from Novus Biologicals
|
||||||||||
Bim Antibody (151-149) [DyLight 680] - NBP1-40988FR from Novus Biologicals
|
||||||||||
Bim(Ser55) Polyclonal Antibody - bs-3058R from Bioss
|
||||||||||
Bcl2l11 Antibody (OASA00014) - OASA00014 from Aviva Systems Biology
|
||||||||||
Bcl2l11 Antibody (OASA00015) - OASA00015 from Aviva Systems Biology
|
||||||||||
Bcl2l11 Antibody (OASA00016) - OASA00016 from Aviva Systems Biology
|
||||||||||
BIM:FITC Antibody (OASA11358) - OASA11358 from Aviva Systems Biology
|