Bcl2l11

Gene Symbol Bcl2l11
Entrez Gene 12125
Alt Symbol 1500006F24Rik, Bim, Bod, bcl2-L-11
Species Mouse
Gene Type protein-coding
Description BCL2-like 11 (apoptosis facilitator)
Other Description Bcl2 interacting mediator of cell death|bcl-2-like protein 11|bcl2-interacting mediator of cell death
Swissprots O54920 O54919 O54918 A2ALQ6
Accessions EDL28212 EDL28213 EDL28214 O54918 AA275665 AA881651 AF032459 AAC40029 AF032460 AAC40030 AF032461 AAC40031 AK011490 AK031285 AK037885 AK050192 AK082613 BAC38548 AK150464 BAE29581 AK152472 BAE31246 AK153542 BAE32079 AK162975 BAE37144 AK177547 BC019556 AAH19556 BC058175 AAH58175 BE136124 CA321725 CB521709 XM_006498614 XP_006498677 XM_006498615 XP_006498678 XM_006498616 XP_006498679 XM_006498617 XP_006498680 NM_001284410 NP_001271339 NM_001291016 NP_001277945 NM_009754 NP_033884 NM_207680 NP_997563 NM_207681 NP_997564
Function Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent. {ECO:0000269|PubMed:9430630}.
Subcellular Location Membrane {ECO:0000269|PubMed:9430630}; Peripheral membrane protein {ECO:0000269|PubMed:9430630}. Mitochondrion {ECO:0000250}. Note=Associated with intracytoplasmic membranes.
Tissue Specificity Expressed in a number of B- and T-lymphoid cell lines. {ECO:0000269|PubMed:9430630}.
Top Pathways PI3K-Akt signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD)

Bim CRISPR/Cas9 KO Plasmid (m) - sc-419332 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim HDR Plasmid (m) - sc-419332-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim Double Nickase Plasmid (m) - sc-419332-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim Double Nickase Plasmid (m2) - sc-419332-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim CRISPR Activation Plasmid (m) - sc-419332-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim CRISPR Activation Plasmid (m2) - sc-419332-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim Lentiviral Activation Particles (m) - sc-419332-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim Lentiviral Activation Particles (m2) - sc-419332-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bim siRNA (m) - sc-29803 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bim shRNA Plasmid (m) - sc-29803-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bim shRNA (m) Lentiviral Particles - sc-29803-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU074771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN27562 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27562 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BCL2L11 siRNA (Mouse) - CRM0383 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BCL2L11 - MBS8215234 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Bcl2l11 (NM_009754.3) - SHH245942 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Bcl2l11(NM_009754.3) - SHG097309 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Bcl2l11(NM_207680.2) - SHG097417 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Bcl2l11(NM_207681.2) - SHG097539 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse BCL2L11 siRNA - orb279859 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BCL2L11 shRNA Plasmid (Mouse) - CHM0383 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

BCL2L11 miRNA 3'UTR clone - MiUTR1M-02162 from Creative biogene

Species Reactivities Mouse

BCL2L11 miRNA 3'UTR clone - MiUTR1M-02163 from Creative biogene

Species Reactivities Mouse
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