Gene Symbol | SRI |
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Entrez Gene | 6717 |
Alt Symbol | CP-22, CP22, SCN, V19 |
Species | Human |
Gene Type | protein-coding |
Description | sorcin |
Other Description | 22 kDa protein|H_RG167B05.1|calcium binding protein amplified in mutlidrug-resistant cells |
Swissprots | B4DKK2 P30626 D6W5Q0 A8MTH6 |
Accessions | AAB96327 EAW76909 EAW76910 EAW76911 P30626 AK129770 AK295225 BAG58218 AK296601 BAG59214 AK310366 AL039198 AL117616 AL576812 BC011025 AAH11025 BI524104 BI559592 BI597920 BM739144 BM793972 BU854353 DA268050 DB540255 L12387 AAA92155 M32886 AAA60588 XM_006716097 XP_006716160 XM_011516528 XP_011514830 NM_001256891 NP_001243820 NM_001256892 NP_001243821 NM_003130 NP_003121 NM_198901 NP_944490 |
Function | Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels. {ECO:0000269|PubMed:17699613}. |
Subcellular Location | Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels. |
Tissue Specificity | Detected in cardiac myocytes. |
SRI-Over-expression-Lysate - LY13618a from Abgent, a WuXi AppTec company
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SRI overexpression lysate - LY403696 from Acris Antibodies
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SRI 293 Cell Lysate - 401014 from ABBIOTEC
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SRI 293 Cell Lysate - 403183 from ABBIOTEC
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SR1 Overexpression Lysate (Native) - NBL1-16450 from Novus Biologicals
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SR1 Overexpression Lysate (Native) - NBL1-16451 from Novus Biologicals
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SRI Over-expression Lysate Product - GWB-D29010 from Genway Biotech
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SRI Over-expression Lysate Product - GWB-83D692 from Genway Biotech
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Human SRI / Sorcin Insect Cell Lysate (WB positive control) - 14547-HNCBL-300 from Sino Biological
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Human SRI / Sorcin Insect Cell Lysate (WB positive control) - 14547-H20BL-300 from Sino Biological
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Human SRI Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175238 from Biorbyt
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Human SRI Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175275 from Biorbyt
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SRI-knockout Cell lysate - LC810226 from Acris Antibodies
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Panoply™ Human SRI Knockdown Stable Cell Line - CSC-DC015151 from Creative biogene
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Human SRI Knockout Cell Line-HeLa - CSC-RT0635 from Creative biogene
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SRI KO Cell Lysate-HeLa - CLKO-0141 from Creative biogene
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