Gene Symbol | RCE1 |
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Entrez Gene | 9986 |
Alt Symbol | FACE2, RCE1A, RCE1B |
Species | Human |
Gene Type | protein-coding |
Description | Ras converting CAAX endopeptidase 1 |
Other Description | CAAX prenyl protease 2|RCE1 homolog, prenyl protein peptidase|farnesylated protein-converting enzyme 2|farnesylated proteins-converting enzyme 2|prenyl protein-specific endoprotease 2 |
Swissprots | Q52LZ9 Q9Y256 |
Accessions | CAH05639 EAW74565 EAW74566 EAW74567 Q9Y256 AF121951 AAD22632 AL713740 BC052622 AAH52622 BC093726 AAH93726 BC093728 AAH93728 Y13835 CAB46278 NM_001032279 NP_001027450 NM_005133 NP_005124 |
Function | Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:19188362}; Multi-pass membrane protein {ECO:0000269|PubMed:19188362}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Terpenoid backbone biosynthesis |
Human RCE1 protein fragment - ab160745 from Abcam
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RCE1 Antibody Blocking Peptide - LS-E16451 from LifeSpan Bioscience
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Recombinant Human RCE1 Protein - H00009986-Q01 from Novus Biologicals
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RCE1 Blocking Peptide - 33R-9934 from Fitzgerald
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RCE1 - H00009986-Q01-10 from Acris Antibodies
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RCE1 - H00009986-Q01-25 from Acris Antibodies
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RCE1 fusion protein - ag12843 from Proteintech Group
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RCE1-Antibody-N-term-W57-Blocking-Peptide - BP2416b from Abgent, a WuXi AppTec company
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RCE1-Antibody-N-term-Blocking-Peptide - BP2416a from Abgent, a WuXi AppTec company
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RCE1 Peptide, Human - M34GP13114H from Creative Peptides
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CAAX prenyl protease 2 (RCE1), Recombinant Protein - MBS7028441 from MyBioSource
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